Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | chrom |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | REACTOME_TRANSCRIPTION |
| Enrichment Score (ES) | 0.432105 |
| Normalized Enrichment Score (NES) | 1.7998788 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.024725366 |
| FWER p-Value | 0.203 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PCF11 | PCF11 Entrez, Source | PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae) | 66 | 2.239 | 0.0146 | Yes |
| 2 | GTF3C2 | GTF3C2 Entrez, Source | general transcription factor IIIC, polypeptide 2, beta 110kDa | 102 | 2.056 | 0.0357 | Yes |
| 3 | SNRPF | SNRPF Entrez, Source | small nuclear ribonucleoprotein polypeptide F | 110 | 2.029 | 0.0649 | Yes |
| 4 | RNGTT | RNGTT Entrez, Source | RNA guanylyltransferase and 5'-phosphatase | 122 | 1.910 | 0.0911 | Yes |
| 5 | TAF1C | TAF1C Entrez, Source | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa | 180 | 1.596 | 0.0984 | Yes |
| 6 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 193 | 1.555 | 0.1188 | Yes |
| 7 | PTRF | PTRF Entrez, Source | polymerase I and transcript release factor | 204 | 1.511 | 0.1391 | Yes |
| 8 | POLRMT | POLRMT Entrez, Source | polymerase (RNA) mitochondrial (DNA directed) | 240 | 1.408 | 0.1502 | Yes |
| 9 | PAPOLA | PAPOLA Entrez, Source | poly(A) polymerase alpha | 246 | 1.396 | 0.1703 | Yes |
| 10 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 247 | 1.393 | 0.1918 | Yes |
| 11 | GTF2E2 | GTF2E2 Entrez, Source | general transcription factor IIE, polypeptide 2, beta 34kDa | 255 | 1.379 | 0.2110 | Yes |
| 12 | POLR2G | POLR2G Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide G | 268 | 1.353 | 0.2283 | Yes |
| 13 | POU2F1 | POU2F1 Entrez, Source | POU domain, class 2, transcription factor 1 | 292 | 1.287 | 0.2412 | Yes |
| 14 | SUPT4H1 | SUPT4H1 Entrez, Source | suppressor of Ty 4 homolog 1 (S. cerevisiae) | 307 | 1.247 | 0.2562 | Yes |
| 15 | EHMT2 | EHMT2 Entrez, Source | euchromatic histone-lysine N-methyltransferase 2 | 387 | 1.103 | 0.2493 | Yes |
| 16 | POLR2I | POLR2I Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 391 | 1.097 | 0.2653 | Yes |
| 17 | TAF9 | TAF9 Entrez, Source | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa | 396 | 1.092 | 0.2810 | Yes |
| 18 | SRSF1 | 475 | 0.974 | 0.2723 | Yes | ||
| 19 | SUPT5H | SUPT5H Entrez, Source | suppressor of Ty 5 homolog (S. cerevisiae) | 485 | 0.960 | 0.2844 | Yes |
| 20 | POLR3C | POLR3C Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide C (62kD) | 515 | 0.926 | 0.2899 | Yes |
| 21 | UBTF | UBTF Entrez, Source | upstream binding transcription factor, RNA polymerase I | 547 | 0.897 | 0.2944 | Yes |
| 22 | NFIB | NFIB Entrez, Source | nuclear factor I/B | 562 | 0.880 | 0.3037 | Yes |
| 23 | POLR2C | POLR2C Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide C, 33kDa | 629 | 0.809 | 0.2962 | Yes |
| 24 | CDK9 | CDK9 Entrez, Source | cyclin-dependent kinase 9 (CDC2-related kinase) | 651 | 0.786 | 0.3020 | Yes |
| 25 | CBX3 | CBX3 Entrez, Source | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | 653 | 0.786 | 0.3138 | Yes |
| 26 | GTF3C4 | GTF3C4 Entrez, Source | general transcription factor IIIC, polypeptide 4, 90kDa | 665 | 0.772 | 0.3224 | Yes |
| 27 | U2AF1 | U2AF1 Entrez, Source | U2 small nuclear RNA auxiliary factor 1 | 677 | 0.762 | 0.3308 | Yes |
| 28 | POLR2F | POLR2F Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide F | 681 | 0.759 | 0.3416 | Yes |
| 29 | CSTF3 | CSTF3 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | 698 | 0.741 | 0.3482 | Yes |
| 30 | SRSF4 | 723 | 0.718 | 0.3520 | Yes | ||
| 31 | SRSF6 | 740 | 0.703 | 0.3580 | Yes | ||
| 32 | TFAM | TFAM Entrez, Source | transcription factor A, mitochondrial | 790 | 0.662 | 0.3534 | Yes |
| 33 | SRSF2 | 836 | 0.628 | 0.3494 | Yes | ||
| 34 | CSTF1 | CSTF1 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 867 | 0.604 | 0.3496 | Yes |
| 35 | CDC40 | CDC40 Entrez, Source | cell division cycle 40 homolog (S. cerevisiae) | 874 | 0.602 | 0.3571 | Yes |
| 36 | CDK7 | CDK7 Entrez, Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 879 | 0.597 | 0.3651 | Yes |
| 37 | TAF6 | TAF6 Entrez, Source | TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa | 888 | 0.589 | 0.3718 | Yes |
| 38 | CPSF7 | 902 | 0.579 | 0.3768 | Yes | ||
| 39 | MBD2 | MBD2 Entrez, Source | methyl-CpG binding domain protein 2 | 904 | 0.578 | 0.3854 | Yes |
| 40 | CPSF2 | CPSF2 Entrez, Source | cleavage and polyadenylation specific factor 2, 100kDa | 947 | 0.555 | 0.3813 | Yes |
| 41 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 970 | 0.539 | 0.3829 | Yes |
| 42 | POLR1C | POLR1C Entrez, Source | polymerase (RNA) I polypeptide C, 30kDa | 972 | 0.538 | 0.3909 | Yes |
| 43 | HIST2H2BE | HIST2H2BE Entrez, Source | histone cluster 2, H2be | 974 | 0.536 | 0.3989 | Yes |
| 44 | SRSF11 | 986 | 0.531 | 0.4037 | Yes | ||
| 45 | HIST2H2AC | HIST2H2AC Entrez, Source | histone cluster 2, H2ac | 1009 | 0.520 | 0.4051 | Yes |
| 46 | POLR2D | POLR2D Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide D | 1035 | 0.507 | 0.4053 | Yes |
| 47 | SRSF7 | 1039 | 0.503 | 0.4122 | Yes | ||
| 48 | DHX38 | DHX38 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 38 | 1048 | 0.496 | 0.4174 | Yes |
| 49 | CSTF2 | CSTF2 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | 1088 | 0.469 | 0.4129 | Yes |
| 50 | H3F3B | H3F3B Entrez, Source | H3 histone, family 3B (H3.3B) | 1121 | 0.447 | 0.4100 | Yes |
| 51 | RBM8A | RBM8A Entrez, Source | RNA binding motif protein 8A | 1126 | 0.445 | 0.4157 | Yes |
| 52 | SRRM1 | SRRM1 Entrez, Source | serine/arginine repetitive matrix 1 | 1162 | 0.423 | 0.4116 | Yes |
| 53 | TAF4 | TAF4 Entrez, Source | TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa | 1164 | 0.421 | 0.4178 | Yes |
| 54 | HIST1H2BL | HIST1H2BL Entrez, Source | histone cluster 1, H2bl | 1178 | 0.414 | 0.4203 | Yes |
| 55 | GTF2E1 | GTF2E1 Entrez, Source | general transcription factor IIE, polypeptide 1, alpha 56kDa | 1182 | 0.413 | 0.4257 | Yes |
| 56 | GTF3C3 | GTF3C3 Entrez, Source | general transcription factor IIIC, polypeptide 3, 102kDa | 1215 | 0.400 | 0.4222 | Yes |
| 57 | HIST1H4A | HIST1H4A Entrez, Source | histone cluster 1, H4a | 1253 | 0.373 | 0.4167 | Yes |
| 58 | POLR2A | POLR2A Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 1258 | 0.369 | 0.4212 | Yes |
| 59 | SRSF9 | 1286 | 0.350 | 0.4184 | Yes | ||
| 60 | TAF5 | TAF5 Entrez, Source | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa | 1290 | 0.349 | 0.4229 | Yes |
| 61 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 1292 | 0.348 | 0.4280 | Yes |
| 62 | GTF3C5 | GTF3C5 Entrez, Source | general transcription factor IIIC, polypeptide 5, 63kDa | 1297 | 0.346 | 0.4321 | Yes |
| 63 | POLR2B | POLR2B Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 1331 | 0.322 | 0.4271 | No |
| 64 | POLR2E | POLR2E Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa | 1411 | 0.275 | 0.4073 | No |
| 65 | RNPS1 | RNPS1 Entrez, Source | RNA binding protein S1, serine-rich domain | 1421 | 0.268 | 0.4088 | No |
| 66 | TCEB1 | TCEB1 Entrez, Source | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 1432 | 0.262 | 0.4098 | No |
| 67 | CPSF1 | CPSF1 Entrez, Source | cleavage and polyadenylation specific factor 1, 160kDa | 1444 | 0.254 | 0.4104 | No |
| 68 | GTF2B | GTF2B Entrez, Source | general transcription factor IIB | 1461 | 0.240 | 0.4092 | No |
| 69 | TCEB3 | TCEB3 Entrez, Source | transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) | 1482 | 0.227 | 0.4067 | No |
| 70 | HIST1H2AC | HIST1H2AC Entrez, Source | histone cluster 1, H2ac | 1520 | 0.197 | 0.3985 | No |
| 71 | CCNH | CCNH Entrez, Source | cyclin H | 1539 | 0.187 | 0.3959 | No |
| 72 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 1545 | 0.185 | 0.3972 | No |
| 73 | POLR2H | POLR2H Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide H | 1550 | 0.183 | 0.3988 | No |
| 74 | TCEB2 | TCEB2 Entrez, Source | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 1584 | 0.161 | 0.3913 | No |
| 75 | GTF2F2 | GTF2F2 Entrez, Source | general transcription factor IIF, polypeptide 2, 30kDa | 1618 | 0.139 | 0.3834 | No |
| 76 | POLR1B | POLR1B Entrez, Source | polymerase (RNA) I polypeptide B, 128kDa | 1638 | 0.125 | 0.3796 | No |
| 77 | POLR2L | POLR2L Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 1670 | 0.109 | 0.3719 | No |
| 78 | POLR2K | POLR2K Entrez, Source | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 1692 | 0.094 | 0.3670 | No |
| 79 | SNRPG | SNRPG Entrez, Source | small nuclear ribonucleoprotein polypeptide G | 1694 | 0.094 | 0.3681 | No |
| 80 | SSRP1 | SSRP1 Entrez, Source | structure specific recognition protein 1 | 1748 | 0.058 | 0.3529 | No |
| 81 | TBP | TBP Entrez, Source | TATA box binding protein | 1772 | 0.047 | 0.3467 | No |
| 82 | CLP1 | 1775 | 0.044 | 0.3467 | No | ||
| 83 | PABPN1 | PABPN1 Entrez, Source | poly(A) binding protein, nuclear 1 | 1777 | 0.043 | 0.3471 | No |
| 84 | POLR1A | POLR1A Entrez, Source | polymerase (RNA) I polypeptide A, 194kDa | 1787 | 0.037 | 0.3449 | No |
| 85 | CPSF3 | CPSF3 Entrez, Source | cleavage and polyadenylation specific factor 3, 73kDa | 1903 | -0.038 | 0.3106 | No |
| 86 | GTF2F1 | GTF2F1 Entrez, Source | general transcription factor IIF, polypeptide 1, 74kDa | 1920 | -0.052 | 0.3066 | No |
| 87 | NCBP2 | NCBP2 Entrez, Source | nuclear cap binding protein subunit 2, 20kDa | 1933 | -0.062 | 0.3039 | No |
| 88 | ERCC3 | ERCC3 Entrez, Source | excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) | 1944 | -0.069 | 0.3019 | No |
| 89 | MAGOH | MAGOH Entrez, Source | mago-nashi homolog, proliferation-associated (Drosophila) | 1973 | -0.086 | 0.2947 | No |
| 90 | UPF3B | UPF3B Entrez, Source | UPF3 regulator of nonsense transcripts homolog B (yeast) | 1979 | -0.089 | 0.2946 | No |
| 91 | SSB | SSB Entrez, Source | Sjogren syndrome antigen B (autoantigen La) | 1981 | -0.090 | 0.2957 | No |
| 92 | GTF2H4 | GTF2H4 Entrez, Source | general transcription factor IIH, polypeptide 4, 52kDa | 2025 | -0.126 | 0.2846 | No |
| 93 | SRSF5 | 2080 | -0.167 | 0.2708 | No | ||
| 94 | SNRPD3 | SNRPD3 Entrez, Source | small nuclear ribonucleoprotein D3 polypeptide 18kDa | 2090 | -0.174 | 0.2707 | No |
| 95 | TAF1A | TAF1A Entrez, Source | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa | 2096 | -0.177 | 0.2719 | No |
| 96 | POLR1D | POLR1D Entrez, Source | polymerase (RNA) I polypeptide D, 16kDa | 2102 | -0.182 | 0.2732 | No |
| 97 | SUPT16H | SUPT16H Entrez, Source | suppressor of Ty 16 homolog (S. cerevisiae) | 2149 | -0.213 | 0.2626 | No |
| 98 | GTF2H3 | GTF2H3 Entrez, Source | general transcription factor IIH, polypeptide 3, 34kDa | 2204 | -0.248 | 0.2500 | No |
| 99 | ERCC2 | ERCC2 Entrez, Source | excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D) | 2224 | -0.262 | 0.2483 | No |
| 100 | SNRPE | SNRPE Entrez, Source | small nuclear ribonucleoprotein polypeptide E | 2256 | -0.284 | 0.2433 | No |
| 101 | TAF1B | TAF1B Entrez, Source | TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa | 2317 | -0.316 | 0.2299 | No |
| 102 | POLR3B | POLR3B Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide B | 2440 | -0.409 | 0.1992 | No |
| 103 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 2471 | -0.439 | 0.1969 | No |
| 104 | TFB2M | TFB2M Entrez, Source | transcription factor B2, mitochondrial | 2595 | -0.534 | 0.1678 | No |
| 105 | TAF10 | TAF10 Entrez, Source | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | 2744 | -0.661 | 0.1331 | No |
| 106 | ELL | ELL Entrez, Source | elongation factor RNA polymerase II | 2858 | -0.800 | 0.1111 | No |
| 107 | GTF2H1 | GTF2H1 Entrez, Source | general transcription factor IIH, polypeptide 1, 62kDa | 2994 | -0.969 | 0.0851 | No |
| 108 | TCEA1 | TCEA1 Entrez, Source | transcription elongation factor A (SII), 1 | 3064 | -1.097 | 0.0811 | No |
| 109 | CCNT1 | CCNT1 Entrez, Source | cyclin T1 | 3202 | -1.372 | 0.0607 | No |
