Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | chrom |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE |
| Enrichment Score (ES) | -0.6414798 |
| Normalized Enrichment Score (NES) | -2.837575 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SRP14 | SRP14 Entrez, Source | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 1016 | 0.513 | -0.2997 | No |
| 2 | RPL13 | RPL13 Entrez, Source | ribosomal protein L13 | 1021 | 0.511 | -0.2936 | No |
| 3 | SEC11C | 1270 | 0.361 | -0.3634 | No | ||
| 4 | RPL32 | RPL32 Entrez, Source | ribosomal protein L32 | 1299 | 0.345 | -0.3668 | No |
| 5 | TRAM1 | TRAM1 Entrez, Source | translocation associated membrane protein 1 | 1581 | 0.163 | -0.4494 | No |
| 6 | RPL26L1 | RPL26L1 Entrez, Source | ribosomal protein L26-like 1 | 1607 | 0.147 | -0.4549 | No |
| 7 | SSR1 | SSR1 Entrez, Source | signal sequence receptor, alpha (translocon-associated protein alpha) | 1621 | 0.138 | -0.4568 | No |
| 8 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 1739 | 0.066 | -0.4912 | No |
| 9 | RPL12 | RPL12 Entrez, Source | ribosomal protein L12 | 1785 | 0.038 | -0.5043 | No |
| 10 | DDOST | DDOST Entrez, Source | dolichyl-diphosphooligosaccharide-protein glycosyltransferase | 1907 | -0.043 | -0.5403 | No |
| 11 | SRP9 | SRP9 Entrez, Source | signal recognition particle 9kDa | 1909 | -0.045 | -0.5399 | No |
| 12 | RPL15 | RPL15 Entrez, Source | ribosomal protein L15 | 1943 | -0.068 | -0.5489 | No |
| 13 | RPL10A | RPL10A Entrez, Source | ribosomal protein L10a | 1954 | -0.075 | -0.5508 | No |
| 14 | RPL18 | RPL18 Entrez, Source | ribosomal protein L18 | 2012 | -0.114 | -0.5664 | No |
| 15 | SSR3 | SSR3 Entrez, Source | signal sequence receptor, gamma (translocon-associated protein gamma) | 2027 | -0.127 | -0.5688 | No |
| 16 | RPN2 | RPN2 Entrez, Source | ribophorin II | 2038 | -0.137 | -0.5699 | No |
| 17 | RPS24 | RPS24 Entrez, Source | ribosomal protein S24 | 2211 | -0.253 | -0.6182 | No |
| 18 | RPL5 | RPL5 Entrez, Source | ribosomal protein L5 | 2234 | -0.269 | -0.6210 | No |
| 19 | SEC61G | SEC61G Entrez, Source | Sec61 gamma subunit | 2235 | -0.269 | -0.6171 | No |
| 20 | SEC61B | SEC61B Entrez, Source | Sec61 beta subunit | 2286 | -0.299 | -0.6279 | No |
| 21 | RPL28 | RPL28 Entrez, Source | ribosomal protein L28 | 2309 | -0.310 | -0.6301 | No |
| 22 | RPN1 | RPN1 Entrez, Source | ribophorin I | 2310 | -0.311 | -0.6256 | No |
| 23 | SPCS3 | SPCS3 Entrez, Source | signal peptidase complex subunit 3 homolog (S. cerevisiae) | 2316 | -0.316 | -0.6226 | No |
| 24 | RPL11 | RPL11 Entrez, Source | ribosomal protein L11 | 2370 | -0.350 | -0.6336 | No |
| 25 | RPL23A | RPL23A Entrez, Source | ribosomal protein L23a | 2397 | -0.373 | -0.6360 | Yes |
| 26 | RPL7A | RPL7A Entrez, Source | ribosomal protein L7a | 2402 | -0.376 | -0.6318 | Yes |
| 27 | SSR4 | SSR4 Entrez, Source | signal sequence receptor, delta (translocon-associated protein delta) | 2414 | -0.386 | -0.6296 | Yes |
| 28 | RPL13A | RPL13A Entrez, Source | ribosomal protein L13a | 2427 | -0.399 | -0.6275 | Yes |
| 29 | RPL29 | RPL29 Entrez, Source | ribosomal protein L29 | 2466 | -0.433 | -0.6327 | Yes |
| 30 | RPL21 | RPL21 Entrez, Source | ribosomal protein L21 | 2496 | -0.455 | -0.6349 | Yes |
| 31 | RPL8 | RPL8 Entrez, Source | ribosomal protein L8 | 2503 | -0.460 | -0.6301 | Yes |
| 32 | RPL27 | RPL27 Entrez, Source | ribosomal protein L27 | 2512 | -0.469 | -0.6258 | Yes |
| 33 | SPCS2 | SPCS2 Entrez, Source | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 2517 | -0.478 | -0.6201 | Yes |
| 34 | RPL14 | RPL14 Entrez, Source | ribosomal protein L14 | 2534 | -0.488 | -0.6179 | Yes |
| 35 | RPL6 | RPL6 Entrez, Source | ribosomal protein L6 | 2569 | -0.516 | -0.6207 | Yes |
| 36 | RPL17 | RPL17 Entrez, Source | ribosomal protein L17 | 2574 | -0.518 | -0.6145 | Yes |
| 37 | RPL18A | RPL18A Entrez, Source | ribosomal protein L18a | 2598 | -0.538 | -0.6137 | Yes |
| 38 | SRPRB | SRPRB Entrez, Source | signal recognition particle receptor, B subunit | 2631 | -0.570 | -0.6151 | Yes |
| 39 | RPL4 | RPL4 Entrez, Source | ribosomal protein L4 | 2632 | -0.572 | -0.6069 | Yes |
| 40 | RPL27A | RPL27A Entrez, Source | ribosomal protein L27a | 2635 | -0.574 | -0.5992 | Yes |
| 41 | SRP68 | SRP68 Entrez, Source | signal recognition particle 68kDa | 2657 | -0.591 | -0.5970 | Yes |
| 42 | RPS8 | RPS8 Entrez, Source | ribosomal protein S8 | 2658 | -0.592 | -0.5885 | Yes |
| 43 | RPL35 | RPL35 Entrez, Source | ribosomal protein L35 | 2691 | -0.615 | -0.5893 | Yes |
| 44 | SPCS1 | SPCS1 Entrez, Source | signal peptidase complex subunit 1 homolog (S. cerevisiae) | 2739 | -0.657 | -0.5940 | Yes |
| 45 | RPL9 | RPL9 Entrez, Source | ribosomal protein L9 | 2754 | -0.671 | -0.5886 | Yes |
| 46 | SEC11A | 2761 | -0.680 | -0.5806 | Yes | ||
| 47 | RPL7 | RPL7 Entrez, Source | ribosomal protein L7 | 2766 | -0.684 | -0.5720 | Yes |
| 48 | RPS15 | RPS15 Entrez, Source | ribosomal protein S15 | 2780 | -0.712 | -0.5656 | Yes |
| 49 | RPS7 | RPS7 Entrez, Source | ribosomal protein S7 | 2811 | -0.746 | -0.5640 | Yes |
| 50 | RPS5 | RPS5 Entrez, Source | ribosomal protein S5 | 2832 | -0.773 | -0.5589 | Yes |
| 51 | RPL30 | RPL30 Entrez, Source | ribosomal protein L30 | 2838 | -0.780 | -0.5491 | Yes |
| 52 | RPSA | RPSA Entrez, Source | ribosomal protein SA | 2843 | -0.783 | -0.5391 | Yes |
| 53 | RPS3A | RPS3A Entrez, Source | ribosomal protein S3A | 2847 | -0.786 | -0.5286 | Yes |
| 54 | RPL24 | RPL24 Entrez, Source | ribosomal protein L24 | 2863 | -0.805 | -0.5216 | Yes |
| 55 | RPL34 | RPL34 Entrez, Source | ribosomal protein L34 | 2865 | -0.809 | -0.5102 | Yes |
| 56 | RPL23 | RPL23 Entrez, Source | ribosomal protein L23 | 2891 | -0.831 | -0.5058 | Yes |
| 57 | RPL35A | RPL35A Entrez, Source | ribosomal protein L35a | 2898 | -0.838 | -0.4955 | Yes |
| 58 | RPL3 | RPL3 Entrez, Source | ribosomal protein L3 | 2902 | -0.843 | -0.4843 | Yes |
| 59 | RPLP0 | RPLP0 Entrez, Source | ribosomal protein, large, P0 | 2912 | -0.858 | -0.4746 | Yes |
| 60 | RPL36 | RPL36 Entrez, Source | ribosomal protein L36 | 2920 | -0.867 | -0.4643 | Yes |
| 61 | RPS13 | RPS13 Entrez, Source | ribosomal protein S13 | 2928 | -0.875 | -0.4538 | Yes |
| 62 | RPS9 | RPS9 Entrez, Source | ribosomal protein S9 | 2930 | -0.876 | -0.4414 | Yes |
| 63 | RPL22 | RPL22 Entrez, Source | ribosomal protein L22 | 2942 | -0.889 | -0.4319 | Yes |
| 64 | SRP72 | SRP72 Entrez, Source | signal recognition particle 72kDa | 2948 | -0.898 | -0.4205 | Yes |
| 65 | RPS10 | RPS10 Entrez, Source | ribosomal protein S10 | 2958 | -0.909 | -0.4101 | Yes |
| 66 | RPL10 | RPL10 Entrez, Source | ribosomal protein L10 | 2961 | -0.912 | -0.3976 | Yes |
| 67 | RPL31 | RPL31 Entrez, Source | ribosomal protein L31 | 2965 | -0.916 | -0.3853 | Yes |
| 68 | RPS25 | RPS25 Entrez, Source | ribosomal protein S25 | 2976 | -0.938 | -0.3748 | Yes |
| 69 | RPS29 | RPS29 Entrez, Source | ribosomal protein S29 | 2989 | -0.964 | -0.3645 | Yes |
| 70 | RPS6 | RPS6 Entrez, Source | ribosomal protein S6 | 2990 | -0.965 | -0.3506 | Yes |
| 71 | RPS3 | RPS3 Entrez, Source | ribosomal protein S3 | 2992 | -0.968 | -0.3369 | Yes |
| 72 | RPS11 | RPS11 Entrez, Source | ribosomal protein S11 | 2996 | -0.971 | -0.3238 | Yes |
| 73 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 3010 | -0.996 | -0.3134 | Yes |
| 74 | FAU | FAU Entrez, Source | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30 | 3011 | -0.998 | -0.2990 | Yes |
| 75 | RPS23 | RPS23 Entrez, Source | ribosomal protein S23 | 3028 | -1.022 | -0.2891 | Yes |
| 76 | RPL38 | RPL38 Entrez, Source | ribosomal protein L38 | 3041 | -1.055 | -0.2776 | Yes |
| 77 | RPS18 | RPS18 Entrez, Source | ribosomal protein S18 | 3053 | -1.078 | -0.2653 | Yes |
| 78 | RPS16 | RPS16 Entrez, Source | ribosomal protein S16 | 3066 | -1.097 | -0.2532 | Yes |
| 79 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 3076 | -1.109 | -0.2399 | Yes |
| 80 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 3083 | -1.121 | -0.2255 | Yes |
| 81 | RPL37A | RPL37A Entrez, Source | ribosomal protein L37a | 3088 | -1.125 | -0.2105 | Yes |
| 82 | RPS4X | RPS4X Entrez, Source | ribosomal protein S4, X-linked | 3097 | -1.137 | -0.1966 | Yes |
| 83 | SRPR | SRPR Entrez, Source | signal recognition particle receptor ('docking protein') | 3099 | -1.142 | -0.1804 | Yes |
| 84 | RPS21 | RPS21 Entrez, Source | ribosomal protein S21 | 3111 | -1.163 | -0.1670 | Yes |
| 85 | SEC61A1 | SEC61A1 Entrez, Source | Sec61 alpha 1 subunit (S. cerevisiae) | 3145 | -1.232 | -0.1592 | Yes |
| 86 | RPS12 | RPS12 Entrez, Source | ribosomal protein S12 | 3149 | -1.236 | -0.1423 | Yes |
| 87 | RPS28 | RPS28 Entrez, Source | ribosomal protein S28 | 3187 | -1.329 | -0.1343 | Yes |
| 88 | RPLP2 | RPLP2 Entrez, Source | ribosomal protein, large, P2 | 3209 | -1.380 | -0.1208 | Yes |
| 89 | RPS15A | RPS15A Entrez, Source | ribosomal protein S15a | 3238 | -1.448 | -0.1084 | Yes |
| 90 | RPL19 | RPL19 Entrez, Source | ribosomal protein L19 | 3243 | -1.476 | -0.0883 | Yes |
| 91 | RPS26 | RPS26 Entrez, Source | ribosomal protein S26 | 3292 | -1.635 | -0.0792 | Yes |
| 92 | RPS20 | RPS20 Entrez, Source | ribosomal protein S20 | 3295 | -1.644 | -0.0561 | Yes |
| 93 | SRP54 | SRP54 Entrez, Source | signal recognition particle 54kDa | 3301 | -1.666 | -0.0336 | Yes |
| 94 | RPS27 | RPS27 Entrez, Source | ribosomal protein S27 (metallopanstimulin 1) | 3354 | -1.987 | -0.0207 | Yes |
| 95 | RPLP1 | RPLP1 Entrez, Source | ribosomal protein, large, P1 | 3377 | -2.423 | 0.0076 | Yes |
