Datasetchrom
PhenotypeNoPhenotypeAvailable
Upregulated in classna_neg
GeneSetREACTOME_SEMAPHORIN_INTERACTIONS
Enrichment Score (ES)-0.5470004
Normalized Enrichment Score (NES)-1.6461015
Nominal p-value0.014354067
FDR q-value0.034024153
FWER p-Value0.552
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_SEMAPHORIN_INTERACTIONS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CDC42CDC42
Entrez,  Source
cell division cycle 42 (GTP binding protein, 25kDa)1981.5230.0390No
2RAC2RAC2
Entrez,  Source
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)3301.1980.0769No
3TLN1TLN1
Entrez,  Source
talin 17190.7210.0084No
4HSP90AA1HSP90AA1
Entrez,  Source
heat shock protein 90kDa alpha (cytosolic), class A member 115310.190-0.2190No
5RHOARHOA
Entrez,  Source
ras homolog gene family, member A16990.091-0.2625No
6CDK5CDK5
Entrez,  Source
cyclin-dependent kinase 517090.082-0.2599No
7ARHGAP3517250.076-0.2595No
8RHOCRHOC
Entrez,  Source
ras homolog gene family, member C1896-0.032-0.3077No
9HSP90AB1HSP90AB1
Entrez,  Source
heat shock protein 90kDa alpha (cytosolic), class B member 11925-0.057-0.3123No
10RAC1RAC1
Entrez,  Source
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)2140-0.209-0.3622No
11RRASRRAS
Entrez,  Source
related RAS viral (r-ras) oncogene homolog2640-0.577-0.4727Yes
12CFL1CFL1
Entrez,  Source
cofilin 1 (non-muscle)2684-0.609-0.4464Yes
13RHOGRHOG
Entrez,  Source
ras homolog gene family, member G (rho G)2918-0.866-0.4599Yes
14MYH10MYH10
Entrez,  Source
myosin, heavy chain 10, non-muscle3214-1.393-0.4579Yes
15MYL6MYL6
Entrez,  Source
myosin, light chain 6, alkali, smooth muscle and non-muscle3340-1.922-0.3718Yes
16ARHGEF12ARHGEF12
Entrez,  Source
Rho guanine nucleotide exchange factor (GEF) 123345-1.954-0.2480Yes
17MYH9MYH9
Entrez,  Source
myosin, heavy chain 9, non-muscle3353-1.984-0.1231Yes
18MYH14MYH14
Entrez,  Source
myosin, heavy chain 143362-2.1450.0118Yes
Table: GSEA details [plain text format]



Fig 2: REACTOME_SEMAPHORIN_INTERACTIONS: Random ES distribution   
Gene set null distribution of ES for REACTOME_SEMAPHORIN_INTERACTIONS