Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | chrom |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ |
| Enrichment Score (ES) | 0.6744367 |
| Normalized Enrichment Score (NES) | 2.5449698 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NDUFA4 | NDUFA4 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa | 9 | 3.447 | 0.0384 | Yes |
| 2 | NDUFS4 | NDUFS4 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 12 | 3.194 | 0.0758 | Yes |
| 3 | NDUFA6 | NDUFA6 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | 23 | 2.843 | 0.1067 | Yes |
| 4 | NDUFS6 | NDUFS6 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | 25 | 2.804 | 0.1398 | Yes |
| 5 | NDUFV2 | NDUFV2 Entrez, Source | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 39 | 2.536 | 0.1661 | Yes |
| 6 | NDUFA7 | NDUFA7 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | 40 | 2.525 | 0.1962 | Yes |
| 7 | COX6B1 | COX6B1 Entrez, Source | cytochrome c oxidase subunit Vib polypeptide 1 (ubiquitous) | 43 | 2.496 | 0.2253 | Yes |
| 8 | NDUFA2 | NDUFA2 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa | 44 | 2.444 | 0.2544 | Yes |
| 9 | NDUFB7 | NDUFB7 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | 46 | 2.423 | 0.2830 | Yes |
| 10 | NDUFA12 | NDUFA12 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 | 49 | 2.411 | 0.3111 | Yes |
| 11 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 53 | 2.397 | 0.3388 | Yes |
| 12 | NDUFA10 | NDUFA10 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 54 | 2.384 | 0.3672 | Yes |
| 13 | COX5B | COX5B Entrez, Source | cytochrome c oxidase subunit Vb | 55 | 2.381 | 0.3955 | Yes |
| 14 | NDUFB9 | NDUFB9 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa | 60 | 2.305 | 0.4218 | Yes |
| 15 | NDUFB1 | NDUFB1 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | 71 | 2.219 | 0.4452 | Yes |
| 16 | NDUFB8 | NDUFB8 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | 93 | 2.088 | 0.4638 | Yes |
| 17 | NDUFB6 | NDUFB6 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 100 | 2.065 | 0.4866 | Yes |
| 18 | NDUFV1 | NDUFV1 Entrez, Source | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | 108 | 2.033 | 0.5087 | Yes |
| 19 | NDUFS5 | NDUFS5 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) | 121 | 1.913 | 0.5279 | Yes |
| 20 | NDUFB3 | NDUFB3 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | 127 | 1.866 | 0.5486 | Yes |
| 21 | NDUFA3 | NDUFA3 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 136 | 1.783 | 0.5675 | Yes |
| 22 | UQCRC2 | UQCRC2 Entrez, Source | ubiquinol-cytochrome c reductase core protein II | 140 | 1.775 | 0.5877 | Yes |
| 23 | NDUFV3 | NDUFV3 Entrez, Source | NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa | 190 | 1.570 | 0.5918 | Yes |
| 24 | NDUFA9 | NDUFA9 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 197 | 1.525 | 0.6081 | Yes |
| 25 | NDUFB4 | NDUFB4 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa | 212 | 1.489 | 0.6217 | Yes |
| 26 | NDUFS3 | NDUFS3 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) | 214 | 1.482 | 0.6390 | Yes |
| 27 | COX6C | COX6C Entrez, Source | cytochrome c oxidase subunit VIc | 230 | 1.430 | 0.6516 | Yes |
| 28 | COX7A2L | COX7A2L Entrez, Source | cytochrome c oxidase subunit VIIa polypeptide 2 like | 270 | 1.348 | 0.6560 | Yes |
| 29 | NDUFC2 | NDUFC2 Entrez, Source | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa | 273 | 1.345 | 0.6714 | Yes |
| 30 | UQCRC1 | UQCRC1 Entrez, Source | ubiquinol-cytochrome c reductase core protein I | 320 | 1.221 | 0.6721 | Yes |
| 31 | NDUFB5 | NDUFB5 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 359 | 1.148 | 0.6744 | Yes |
| 32 | NDUFB10 | NDUFB10 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa | 454 | 0.996 | 0.6582 | No |
| 33 | NDUFS8 | NDUFS8 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | 467 | 0.984 | 0.6663 | No |
| 34 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 533 | 0.910 | 0.6577 | No |
| 35 | UQCRFS1 | UQCRFS1 Entrez, Source | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | 540 | 0.907 | 0.6667 | No |
| 36 | UQCRB | UQCRB Entrez, Source | ubiquinol-cytochrome c reductase binding protein | 726 | 0.716 | 0.6198 | No |
| 37 | NDUFS7 | NDUFS7 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 738 | 0.704 | 0.6249 | No |
| 38 | UQCRQ | UQCRQ Entrez, Source | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | 793 | 0.661 | 0.6166 | No |
| 39 | NDUFS2 | NDUFS2 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 843 | 0.620 | 0.6093 | No |
| 40 | ATP5C1 | ATP5C1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 | 927 | 0.562 | 0.5912 | No |
| 41 | NDUFA13 | NDUFA13 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 | 931 | 0.561 | 0.5969 | No |
| 42 | CYC1 | CYC1 Entrez, Source | cytochrome c-1 | 943 | 0.556 | 0.6003 | No |
| 43 | NDUFA8 | NDUFA8 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa | 981 | 0.534 | 0.5956 | No |
| 44 | SDHB | SDHB Entrez, Source | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 983 | 0.532 | 0.6016 | No |
| 45 | COX4I1 | COX4I1 Entrez, Source | cytochrome c oxidase subunit IV isoform 1 | 1038 | 0.504 | 0.5914 | No |
| 46 | NDUFA5 | NDUFA5 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa | 1085 | 0.471 | 0.5833 | No |
| 47 | ATP5L | ATP5L Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G | 1166 | 0.420 | 0.5643 | No |
| 48 | ETFDH | ETFDH Entrez, Source | electron-transferring-flavoprotein dehydrogenase | 1167 | 0.419 | 0.5693 | No |
| 49 | ATP5F1 | ATP5F1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1 | 1188 | 0.409 | 0.5682 | No |
| 50 | ATP5J2 | ATP5J2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2 | 1217 | 0.399 | 0.5646 | No |
| 51 | ATP5O | ATP5O Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 1387 | 0.291 | 0.5174 | No |
| 52 | ATP5B | ATP5B Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide | 1396 | 0.283 | 0.5184 | No |
| 53 | ATP5H | ATP5H Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d | 1473 | 0.233 | 0.4984 | No |
| 54 | ATP5A1 | ATP5A1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle | 1526 | 0.193 | 0.4852 | No |
| 55 | ATP5J | ATP5J Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 | 1548 | 0.184 | 0.4811 | No |
| 56 | COX5A | COX5A Entrez, Source | cytochrome c oxidase subunit Va | 1661 | 0.114 | 0.4489 | No |
| 57 | ATP5D | ATP5D Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 1790 | 0.037 | 0.4110 | No |
| 58 | ETFB | ETFB Entrez, Source | electron-transfer-flavoprotein, beta polypeptide | 1924 | -0.055 | 0.3718 | No |
| 59 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 2617 | -0.560 | 0.1713 | No |
| 60 | ETFA | ETFA Entrez, Source | electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) | 2767 | -0.692 | 0.1350 | No |
| 61 | UQCRH | UQCRH Entrez, Source | ubiquinol-cytochrome c reductase hinge protein | 2908 | -0.852 | 0.1032 | No |
| 62 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 3167 | -1.278 | 0.0412 | No |
| 63 | ATP5I | ATP5I Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E | 3378 | -2.426 | 0.0072 | No |
