Details for gene set REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE

Table: GSEA Results Summary

Dataset	chrom
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
Enrichment Score (ES)	0.418424
Normalized Enrichment Score (NES)	1.786582
Nominal p-value	0.0
FDR q-value	0.025967523
FWER p-Value	0.229

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PCF11	PCF11 Entrez, Source	PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)	66	2.239	0.0145	Yes
2	SNRPF	SNRPF Entrez, Source	small nuclear ribonucleoprotein polypeptide F	110	2.029	0.0329	Yes
3	PAPOLA	PAPOLA Entrez, Source	poly(A) polymerase alpha	246	1.396	0.0133	Yes
4	POLR2G	POLR2G Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide G	268	1.353	0.0279	Yes
5	FUS	FUS Entrez, Source	fusion (involved in t(12;16) in malignant liposarcoma)	323	1.218	0.0302	Yes
6	PCBP1	PCBP1 Entrez, Source	poly(rC) binding protein 1	338	1.186	0.0443	Yes
7	PCBP2	PCBP2 Entrez, Source	poly(rC) binding protein 2	361	1.144	0.0554	Yes
8	NUP50	NUP50 Entrez, Source	nucleoporin 50kDa	383	1.108	0.0661	Yes
9	POLR2I	POLR2I Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa	391	1.097	0.0810	Yes
10	CD2BP2	CD2BP2 Entrez, Source	CD2 (cytoplasmic tail) binding protein 2	406	1.076	0.0934	Yes
11	HNRNPD			431	1.023	0.1019	Yes
12	SRSF1			475	0.974	0.1039	Yes
13	SNRPA1	SNRPA1 Entrez, Source	small nuclear ribonucleoprotein polypeptide A'	509	0.933	0.1083	Yes
14	RBM5	RBM5 Entrez, Source	RNA binding motif protein 5	514	0.928	0.1215	Yes
15	HNRNPA1			565	0.876	0.1198	Yes
16	HNRNPF			612	0.828	0.1186	Yes
17	POLR2C	POLR2C Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	629	0.809	0.1262	Yes
18	HNRNPK			639	0.802	0.1359	Yes
19	RAE1	RAE1 Entrez, Source	RAE1 RNA export 1 homolog (S. pombe)	646	0.792	0.1464	Yes
20	U2AF1	U2AF1 Entrez, Source	U2 small nuclear RNA auxiliary factor 1	677	0.762	0.1490	Yes
21	POLR2F	POLR2F Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide F	681	0.759	0.1599	Yes
22	CSTF3	CSTF3 Entrez, Source	cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa	698	0.741	0.1664	Yes
23	HNRNPH1			699	0.741	0.1779	Yes
24	HNRNPR			712	0.728	0.1855	Yes
25	SRSF4			723	0.718	0.1936	Yes
26	SRSF6			740	0.703	0.1996	Yes
27	SNRPB2	SNRPB2 Entrez, Source	small nuclear ribonucleoprotein polypeptide B''	756	0.687	0.2057	Yes
28	SF3A2	SF3A2 Entrez, Source	splicing factor 3a, subunit 2, 66kDa	812	0.644	0.1989	Yes
29	SRSF2			836	0.628	0.2016	Yes
30	DHX9	DHX9 Entrez, Source	DEAH (Asp-Glu-Ala-His) box polypeptide 9	837	0.628	0.2113	Yes
31	SUGP1			844	0.619	0.2191	Yes
32	SNRPA	SNRPA Entrez, Source	small nuclear ribonucleoprotein polypeptide A	846	0.618	0.2284	Yes
33	HNRNPH2			849	0.618	0.2373	Yes
34	CSTF1	CSTF1 Entrez, Source	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa	867	0.604	0.2415	Yes
35	RBMX	RBMX Entrez, Source	RNA binding motif protein, X-linked	872	0.603	0.2496	Yes
36	CDC40	CDC40 Entrez, Source	cell division cycle 40 homolog (S. cerevisiae)	874	0.602	0.2587	Yes
37	HNRNPA0			889	0.589	0.2635	Yes
38	SF3A3	SF3A3 Entrez, Source	splicing factor 3a, subunit 3, 60kDa	899	0.582	0.2698	Yes
39	HNRNPA2B1			900	0.581	0.2788	Yes
40	CPSF7			902	0.579	0.2875	Yes
41	NUPL1	NUPL1 Entrez, Source	nucleoporin like 1	907	0.577	0.2952	Yes
42	SF3B4	SF3B4 Entrez, Source	splicing factor 3b, subunit 4, 49kDa	912	0.569	0.3028	Yes
43	HNRNPA3			937	0.558	0.3041	Yes
44	CPSF2	CPSF2 Entrez, Source	cleavage and polyadenylation specific factor 2, 100kDa	947	0.555	0.3100	Yes
45	DNAJC8	DNAJC8 Entrez, Source	DnaJ (Hsp40) homolog, subfamily C, member 8	948	0.555	0.3186	Yes
46	NUDT21	NUDT21 Entrez, Source	nudix (nucleoside diphosphate linked moiety X)-type motif 21	970	0.539	0.3205	Yes
47	SRSF11			986	0.531	0.3241	Yes
48	SF3B3	SF3B3 Entrez, Source	splicing factor 3b, subunit 3, 130kDa	1011	0.518	0.3248	Yes
49	POLR2D	POLR2D Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide D	1035	0.507	0.3257	Yes
50	SRSF7			1039	0.503	0.3326	Yes
51	CCAR1	CCAR1 Entrez, Source	cell division cycle and apoptosis regulator 1	1044	0.497	0.3390	Yes
52	AAAS	AAAS Entrez, Source	achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)	1047	0.496	0.3461	Yes
53	DHX38	DHX38 Entrez, Source	DEAH (Asp-Glu-Ala-His) box polypeptide 38	1048	0.496	0.3538	Yes
54	HNRNPM			1065	0.487	0.3565	Yes
55	PTBP1	PTBP1 Entrez, Source	polypyrimidine tract binding protein 1	1078	0.480	0.3603	Yes
56	CSTF2	CSTF2 Entrez, Source	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa	1088	0.469	0.3648	Yes
57	NUP37	NUP37 Entrez, Source	nucleoporin 37kDa	1102	0.460	0.3679	Yes
58	RBM8A	RBM8A Entrez, Source	RNA binding motif protein 8A	1126	0.445	0.3678	Yes
59	NUP88	NUP88 Entrez, Source	nucleoporin 88kDa	1129	0.444	0.3741	Yes
60	SRRM1	SRRM1 Entrez, Source	serine/arginine repetitive matrix 1	1162	0.423	0.3709	Yes
61	NUP85	NUP85 Entrez, Source	nucleoporin 85kDa	1175	0.416	0.3736	Yes
62	YBX1	YBX1 Entrez, Source	Y box binding protein 1	1192	0.409	0.3751	Yes
63	NUP133	NUP133 Entrez, Source	nucleoporin 133kDa	1203	0.404	0.3783	Yes
64	NUP214	NUP214 Entrez, Source	nucleoporin 214kDa	1209	0.403	0.3830	Yes
65	PRPF4	PRPF4 Entrez, Source	PRP4 pre-mRNA processing factor 4 homolog (yeast)	1236	0.385	0.3811	Yes
66	SNRNP70			1246	0.377	0.3841	Yes
67	POLR2A	POLR2A Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	1258	0.369	0.3865	Yes
68	NUP93	NUP93 Entrez, Source	nucleoporin 93kDa	1268	0.362	0.3894	Yes
69	NUP188	NUP188 Entrez, Source	nucleoporin 188kDa	1273	0.360	0.3937	Yes
70	SF3B5	SF3B5 Entrez, Source	splicing factor 3b, subunit 5, 10kDa	1277	0.356	0.3983	Yes
71	SRSF9			1286	0.350	0.4013	Yes
72	NCBP1	NCBP1 Entrez, Source	nuclear cap binding protein subunit 1, 80kDa	1292	0.348	0.4052	Yes
73	NUP205	NUP205 Entrez, Source	nucleoporin 205kDa	1320	0.330	0.4020	Yes
74	SF3B2	SF3B2 Entrez, Source	splicing factor 3b, subunit 2, 145kDa	1321	0.330	0.4072	Yes
75	POLR2B	POLR2B Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	1331	0.322	0.4094	Yes
76	SMC1A	SMC1A Entrez, Source	structural maintenance of chromosomes 1A	1342	0.315	0.4112	Yes
77	SF3A1	SF3A1 Entrez, Source	splicing factor 3a, subunit 1, 120kDa	1346	0.312	0.4151	Yes
78	NUP107	NUP107 Entrez, Source	nucleoporin 107kDa	1352	0.310	0.4184	Yes
79	SNRNP40			1394	0.285	0.4103	No
80	POLR2E	POLR2E Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	1411	0.275	0.4097	No
81	RNPS1	RNPS1 Entrez, Source	RNA binding protein S1, serine-rich domain	1421	0.268	0.4111	No
82	SF3B14	SF3B14 Entrez, Source	-	1427	0.266	0.4137	No
83	NUP155	NUP155 Entrez, Source	nucleoporin 155kDa	1438	0.259	0.4147	No
84	CPSF1	CPSF1 Entrez, Source	cleavage and polyadenylation specific factor 1, 160kDa	1444	0.254	0.4171	No
85	HNRNPL			1465	0.240	0.4147	No
86	NUP54	NUP54 Entrez, Source	nucleoporin 54kDa	1480	0.228	0.4140	No
87	PRPF8	PRPF8 Entrez, Source	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)	1485	0.225	0.4162	No
88	SEH1L	SEH1L Entrez, Source	SEH1-like (S. cerevisiae)	1507	0.207	0.4130	No
89	NXF1	NXF1 Entrez, Source	nuclear RNA export factor 1	1542	0.187	0.4055	No
90	U2AF2	U2AF2 Entrez, Source	U2 small nuclear RNA auxiliary factor 2	1545	0.185	0.4078	No
91	POLR2H	POLR2H Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide H	1550	0.183	0.4094	No
92	NUP62	NUP62 Entrez, Source	nucleoporin 62kDa	1575	0.166	0.4046	No
93	HNRNPU			1586	0.160	0.4041	No
94	SNRNP200			1616	0.140	0.3974	No
95	GTF2F2	GTF2F2 Entrez, Source	general transcription factor IIF, polypeptide 2, 30kDa	1618	0.139	0.3992	No
96	PRPF6	PRPF6 Entrez, Source	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	1655	0.117	0.3900	No
97	SF3B1	SF3B1 Entrez, Source	splicing factor 3b, subunit 1, 155kDa	1659	0.114	0.3909	No
98	POLR2L	POLR2L Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	1670	0.109	0.3895	No
99	SNRPD1	SNRPD1 Entrez, Source	small nuclear ribonucleoprotein D1 polypeptide 16kDa	1674	0.106	0.3903	No
100	POLR2K	POLR2K Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	1692	0.094	0.3865	No
101	SNRPG	SNRPG Entrez, Source	small nuclear ribonucleoprotein polypeptide G	1694	0.094	0.3877	No
102	NUPL2	NUPL2 Entrez, Source	nucleoporin like 2	1697	0.093	0.3885	No
103	TPR	TPR Entrez, Source	translocated promoter region (to activated MET oncogene)	1726	0.075	0.3811	No
104	TXNL4A	TXNL4A Entrez, Source	thioredoxin-like 4A	1762	0.052	0.3712	No
105	DDX23	DDX23 Entrez, Source	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	1768	0.049	0.3705	No
106	CLP1			1775	0.044	0.3693	No
107	PABPN1	PABPN1 Entrez, Source	poly(A) binding protein, nuclear 1	1777	0.043	0.3697	No
108	PHF5A	PHF5A Entrez, Source	PHD finger protein 5A	1875	-0.016	0.3403	No
109	CPSF3	CPSF3 Entrez, Source	cleavage and polyadenylation specific factor 3, 73kDa	1903	-0.038	0.3326	No
110	GTF2F1	GTF2F1 Entrez, Source	general transcription factor IIF, polypeptide 1, 74kDa	1920	-0.052	0.3286	No
111	NCBP2	NCBP2 Entrez, Source	nuclear cap binding protein subunit 2, 20kDa	1933	-0.062	0.3259	No
112	EIF4E	EIF4E Entrez, Source	eukaryotic translation initiation factor 4E	1971	-0.086	0.3159	No
113	MAGOH	MAGOH Entrez, Source	mago-nashi homolog, proliferation-associated (Drosophila)	1973	-0.086	0.3169	No
114	UPF3B	UPF3B Entrez, Source	UPF3 regulator of nonsense transcripts homolog B (yeast)	1979	-0.089	0.3168	No
115	NUP43	NUP43 Entrez, Source	nucleoporin 43kDa	1986	-0.096	0.3164	No
116	HNRNPUL1			2056	-0.150	0.2977	No
117	SRSF5			2080	-0.167	0.2932	No
118	SNRPD3	SNRPD3 Entrez, Source	small nuclear ribonucleoprotein D3 polypeptide 18kDa	2090	-0.174	0.2932	No
119	EFTUD2	EFTUD2 Entrez, Source	elongation factor Tu GTP binding domain containing 2	2183	-0.235	0.2687	No
120	SNRPE	SNRPE Entrez, Source	small nuclear ribonucleoprotein polypeptide E	2256	-0.284	0.2511	No
121	SNRPD2	SNRPD2 Entrez, Source	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	2407	-0.379	0.2112	No
122	METTL3	METTL3 Entrez, Source	methyltransferase like 3	2488	-0.452	0.1938	No
123	NUP153	NUP153 Entrez, Source	nucleoporin 153kDa	2537	-0.489	0.1867	No
124	RANBP2	RANBP2 Entrez, Source	RAN binding protein 2	2542	-0.493	0.1931	No
125	NUP210	NUP210 Entrez, Source	nucleoporin 210kDa	2747	-0.665	0.1411	No
126	NHP2L1	NHP2L1 Entrez, Source	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)	2770	-0.694	0.1452	No
127	NUP35	NUP35 Entrez, Source	nucleoporin 35kDa	2894	-0.835	0.1205	No
128	HNRNPC			2988	-0.959	0.1070	No
129	LSM2	LSM2 Entrez, Source	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	3148	-1.235	0.0776	No