Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | chrom |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX |
| Enrichment Score (ES) | -0.6370299 |
| Normalized Enrichment Score (NES) | -2.7739644 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PPP2R1A | PPP2R1A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | 914 | 0.569 | -0.2665 | No |
| 2 | RPL13 | RPL13 Entrez, Source | ribosomal protein L13 | 1021 | 0.511 | -0.2903 | No |
| 3 | EIF4A3 | 1110 | 0.455 | -0.3096 | No | ||
| 4 | RBM8A | RBM8A Entrez, Source | RNA binding motif protein 8A | 1126 | 0.445 | -0.3071 | No |
| 5 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 1292 | 0.348 | -0.3513 | No |
| 6 | RPL32 | RPL32 Entrez, Source | ribosomal protein L32 | 1299 | 0.345 | -0.3476 | No |
| 7 | RNPS1 | RNPS1 Entrez, Source | RNA binding protein S1, serine-rich domain | 1421 | 0.268 | -0.3798 | No |
| 8 | PPP2CA | PPP2CA Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 1593 | 0.158 | -0.4289 | No |
| 9 | RPL26L1 | RPL26L1 Entrez, Source | ribosomal protein L26-like 1 | 1607 | 0.147 | -0.4305 | No |
| 10 | ETF1 | ETF1 Entrez, Source | eukaryotic translation termination factor 1 | 1662 | 0.113 | -0.4449 | No |
| 11 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 1739 | 0.066 | -0.4668 | No |
| 12 | RPL12 | RPL12 Entrez, Source | ribosomal protein L12 | 1785 | 0.038 | -0.4798 | No |
| 13 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 1813 | 0.026 | -0.4875 | No |
| 14 | NCBP2 | NCBP2 Entrez, Source | nuclear cap binding protein subunit 2, 20kDa | 1933 | -0.062 | -0.5224 | No |
| 15 | RPL15 | RPL15 Entrez, Source | ribosomal protein L15 | 1943 | -0.068 | -0.5240 | No |
| 16 | RPL10A | RPL10A Entrez, Source | ribosomal protein L10a | 1954 | -0.075 | -0.5258 | No |
| 17 | MAGOH | MAGOH Entrez, Source | mago-nashi homolog, proliferation-associated (Drosophila) | 1973 | -0.086 | -0.5299 | No |
| 18 | UPF3B | UPF3B Entrez, Source | UPF3 regulator of nonsense transcripts homolog B (yeast) | 1979 | -0.089 | -0.5300 | No |
| 19 | RPL18 | RPL18 Entrez, Source | ribosomal protein L18 | 2012 | -0.114 | -0.5378 | No |
| 20 | RPS24 | RPS24 Entrez, Source | ribosomal protein S24 | 2211 | -0.253 | -0.5935 | No |
| 21 | RPL5 | RPL5 Entrez, Source | ribosomal protein L5 | 2234 | -0.269 | -0.5958 | No |
| 22 | RPL28 | RPL28 Entrez, Source | ribosomal protein L28 | 2309 | -0.310 | -0.6132 | No |
| 23 | RPL11 | RPL11 Entrez, Source | ribosomal protein L11 | 2370 | -0.350 | -0.6257 | No |
| 24 | RPL23A | RPL23A Entrez, Source | ribosomal protein L23a | 2397 | -0.373 | -0.6276 | No |
| 25 | RPL7A | RPL7A Entrez, Source | ribosomal protein L7a | 2402 | -0.376 | -0.6228 | No |
| 26 | RPL13A | RPL13A Entrez, Source | ribosomal protein L13a | 2427 | -0.399 | -0.6237 | No |
| 27 | RPL29 | RPL29 Entrez, Source | ribosomal protein L29 | 2466 | -0.433 | -0.6283 | No |
| 28 | RPL21 | RPL21 Entrez, Source | ribosomal protein L21 | 2496 | -0.455 | -0.6298 | Yes |
| 29 | RPL8 | RPL8 Entrez, Source | ribosomal protein L8 | 2503 | -0.460 | -0.6243 | Yes |
| 30 | RPL27 | RPL27 Entrez, Source | ribosomal protein L27 | 2512 | -0.469 | -0.6192 | Yes |
| 31 | RPL14 | RPL14 Entrez, Source | ribosomal protein L14 | 2534 | -0.488 | -0.6178 | Yes |
| 32 | RPL6 | RPL6 Entrez, Source | ribosomal protein L6 | 2569 | -0.516 | -0.6199 | Yes |
| 33 | RPL17 | RPL17 Entrez, Source | ribosomal protein L17 | 2574 | -0.518 | -0.6128 | Yes |
| 34 | RPL18A | RPL18A Entrez, Source | ribosomal protein L18a | 2598 | -0.538 | -0.6112 | Yes |
| 35 | RPL4 | RPL4 Entrez, Source | ribosomal protein L4 | 2632 | -0.572 | -0.6121 | Yes |
| 36 | RPL27A | RPL27A Entrez, Source | ribosomal protein L27a | 2635 | -0.574 | -0.6035 | Yes |
| 37 | RPS8 | RPS8 Entrez, Source | ribosomal protein S8 | 2658 | -0.592 | -0.6007 | Yes |
| 38 | RPL35 | RPL35 Entrez, Source | ribosomal protein L35 | 2691 | -0.615 | -0.6006 | Yes |
| 39 | RPL9 | RPL9 Entrez, Source | ribosomal protein L9 | 2754 | -0.671 | -0.6086 | Yes |
| 40 | RPL7 | RPL7 Entrez, Source | ribosomal protein L7 | 2766 | -0.684 | -0.6011 | Yes |
| 41 | RPS15 | RPS15 Entrez, Source | ribosomal protein S15 | 2780 | -0.712 | -0.5937 | Yes |
| 42 | RPS7 | RPS7 Entrez, Source | ribosomal protein S7 | 2811 | -0.746 | -0.5908 | Yes |
| 43 | RPS5 | RPS5 Entrez, Source | ribosomal protein S5 | 2832 | -0.773 | -0.5846 | Yes |
| 44 | RPL30 | RPL30 Entrez, Source | ribosomal protein L30 | 2838 | -0.780 | -0.5737 | Yes |
| 45 | RPSA | RPSA Entrez, Source | ribosomal protein SA | 2843 | -0.783 | -0.5624 | Yes |
| 46 | RPS3A | RPS3A Entrez, Source | ribosomal protein S3A | 2847 | -0.786 | -0.5508 | Yes |
| 47 | RPL24 | RPL24 Entrez, Source | ribosomal protein L24 | 2863 | -0.805 | -0.5425 | Yes |
| 48 | RPL34 | RPL34 Entrez, Source | ribosomal protein L34 | 2865 | -0.809 | -0.5300 | Yes |
| 49 | RPL23 | RPL23 Entrez, Source | ribosomal protein L23 | 2891 | -0.831 | -0.5243 | Yes |
| 50 | RPL35A | RPL35A Entrez, Source | ribosomal protein L35a | 2898 | -0.838 | -0.5128 | Yes |
| 51 | RPL3 | RPL3 Entrez, Source | ribosomal protein L3 | 2902 | -0.843 | -0.5003 | Yes |
| 52 | RPLP0 | RPLP0 Entrez, Source | ribosomal protein, large, P0 | 2912 | -0.858 | -0.4894 | Yes |
| 53 | RPL36 | RPL36 Entrez, Source | ribosomal protein L36 | 2920 | -0.867 | -0.4777 | Yes |
| 54 | RPS13 | RPS13 Entrez, Source | ribosomal protein S13 | 2928 | -0.875 | -0.4659 | Yes |
| 55 | RPS9 | RPS9 Entrez, Source | ribosomal protein S9 | 2930 | -0.876 | -0.4522 | Yes |
| 56 | RPL22 | RPL22 Entrez, Source | ribosomal protein L22 | 2942 | -0.889 | -0.4414 | Yes |
| 57 | RPS10 | RPS10 Entrez, Source | ribosomal protein S10 | 2958 | -0.909 | -0.4315 | Yes |
| 58 | RPL10 | RPL10 Entrez, Source | ribosomal protein L10 | 2961 | -0.912 | -0.4176 | Yes |
| 59 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 2964 | -0.915 | -0.4036 | Yes |
| 60 | RPL31 | RPL31 Entrez, Source | ribosomal protein L31 | 2965 | -0.916 | -0.3890 | Yes |
| 61 | RPS25 | RPS25 Entrez, Source | ribosomal protein S25 | 2976 | -0.938 | -0.3771 | Yes |
| 62 | RPS29 | RPS29 Entrez, Source | ribosomal protein S29 | 2989 | -0.964 | -0.3654 | Yes |
| 63 | RPS6 | RPS6 Entrez, Source | ribosomal protein S6 | 2990 | -0.965 | -0.3501 | Yes |
| 64 | RPS3 | RPS3 Entrez, Source | ribosomal protein S3 | 2992 | -0.968 | -0.3350 | Yes |
| 65 | RPS11 | RPS11 Entrez, Source | ribosomal protein S11 | 2996 | -0.971 | -0.3204 | Yes |
| 66 | UPF2 | UPF2 Entrez, Source | UPF2 regulator of nonsense transcripts homolog (yeast) | 3002 | -0.983 | -0.3063 | Yes |
| 67 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 3010 | -0.996 | -0.2926 | Yes |
| 68 | FAU | FAU Entrez, Source | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30 | 3011 | -0.998 | -0.2767 | Yes |
| 69 | RPS23 | RPS23 Entrez, Source | ribosomal protein S23 | 3028 | -1.022 | -0.2652 | Yes |
| 70 | RPL38 | RPL38 Entrez, Source | ribosomal protein L38 | 3041 | -1.055 | -0.2521 | Yes |
| 71 | RPS18 | RPS18 Entrez, Source | ribosomal protein S18 | 3053 | -1.078 | -0.2382 | Yes |
| 72 | RPS16 | RPS16 Entrez, Source | ribosomal protein S16 | 3066 | -1.097 | -0.2244 | Yes |
| 73 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 3076 | -1.109 | -0.2095 | Yes |
| 74 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 3083 | -1.121 | -0.1935 | Yes |
| 75 | RPL37A | RPL37A Entrez, Source | ribosomal protein L37a | 3088 | -1.125 | -0.1768 | Yes |
| 76 | RPS4X | RPS4X Entrez, Source | ribosomal protein S4, X-linked | 3097 | -1.137 | -0.1611 | Yes |
| 77 | RPS21 | RPS21 Entrez, Source | ribosomal protein S21 | 3111 | -1.163 | -0.1465 | Yes |
| 78 | RPS12 | RPS12 Entrez, Source | ribosomal protein S12 | 3149 | -1.236 | -0.1380 | Yes |
| 79 | RPS28 | RPS28 Entrez, Source | ribosomal protein S28 | 3187 | -1.329 | -0.1280 | Yes |
| 80 | RPLP2 | RPLP2 Entrez, Source | ribosomal protein, large, P2 | 3209 | -1.380 | -0.1124 | Yes |
| 81 | RPS15A | RPS15A Entrez, Source | ribosomal protein S15a | 3238 | -1.448 | -0.0978 | Yes |
| 82 | RPL19 | RPL19 Entrez, Source | ribosomal protein L19 | 3243 | -1.476 | -0.0756 | Yes |
| 83 | RPS26 | RPS26 Entrez, Source | ribosomal protein S26 | 3292 | -1.635 | -0.0640 | Yes |
| 84 | RPS20 | RPS20 Entrez, Source | ribosomal protein S20 | 3295 | -1.644 | -0.0385 | Yes |
| 85 | RPS27 | RPS27 Entrez, Source | ribosomal protein S27 (metallopanstimulin 1) | 3354 | -1.987 | -0.0244 | Yes |
| 86 | RPLP1 | RPLP1 Entrez, Source | ribosomal protein, large, P1 | 3377 | -2.423 | 0.0075 | Yes |
