Details for gene set REACTOME_MRNA

Table: GSEA Results Summary

Dataset	chrom
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	REACTOME_MRNA_SPLICING
Enrichment Score (ES)	0.46148476
Normalized Enrichment Score (NES)	1.9016612
Nominal p-value	0.0
FDR q-value	0.010182829
FWER p-Value	0.074

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PCF11	PCF11 Entrez, Source	PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)	66	2.239	0.0217	Yes
2	SNRPF	SNRPF Entrez, Source	small nuclear ribonucleoprotein polypeptide F	110	2.029	0.0464	Yes
3	PAPOLA	PAPOLA Entrez, Source	poly(A) polymerase alpha	246	1.396	0.0315	Yes
4	POLR2G	POLR2G Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide G	268	1.353	0.0504	Yes
5	FUS	FUS Entrez, Source	fusion (involved in t(12;16) in malignant liposarcoma)	323	1.218	0.0567	Yes
6	PCBP1	PCBP1 Entrez, Source	poly(rC) binding protein 1	338	1.186	0.0745	Yes
7	PCBP2	PCBP2 Entrez, Source	poly(rC) binding protein 2	361	1.144	0.0892	Yes
8	POLR2I	POLR2I Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa	391	1.097	0.1008	Yes
9	CD2BP2	CD2BP2 Entrez, Source	CD2 (cytoplasmic tail) binding protein 2	406	1.076	0.1166	Yes
10	HNRNPD			431	1.023	0.1284	Yes
11	SRSF1			475	0.974	0.1335	Yes
12	SNRPA1	SNRPA1 Entrez, Source	small nuclear ribonucleoprotein polypeptide A'	509	0.933	0.1409	Yes
13	RBM5	RBM5 Entrez, Source	RNA binding motif protein 5	514	0.928	0.1569	Yes
14	HNRNPA1			565	0.876	0.1581	Yes
15	HNRNPF			612	0.828	0.1596	Yes
16	POLR2C	POLR2C Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	629	0.809	0.1698	Yes
17	HNRNPK			639	0.802	0.1820	Yes
18	U2AF1	U2AF1 Entrez, Source	U2 small nuclear RNA auxiliary factor 1	677	0.762	0.1850	Yes
19	POLR2F	POLR2F Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide F	681	0.759	0.1982	Yes
20	CSTF3	CSTF3 Entrez, Source	cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa	698	0.741	0.2071	Yes
21	HNRNPH1			699	0.741	0.2209	Yes
22	HNRNPR			712	0.728	0.2308	Yes
23	SRSF4			723	0.718	0.2412	Yes
24	SRSF6			740	0.703	0.2494	Yes
25	SNRPB2	SNRPB2 Entrez, Source	small nuclear ribonucleoprotein polypeptide B''	756	0.687	0.2577	Yes
26	SF3A2	SF3A2 Entrez, Source	splicing factor 3a, subunit 2, 66kDa	812	0.644	0.2530	Yes
27	SRSF2			836	0.628	0.2577	Yes
28	DHX9	DHX9 Entrez, Source	DEAH (Asp-Glu-Ala-His) box polypeptide 9	837	0.628	0.2694	Yes
29	SUGP1			844	0.619	0.2791	Yes
30	SNRPA	SNRPA Entrez, Source	small nuclear ribonucleoprotein polypeptide A	846	0.618	0.2903	Yes
31	HNRNPH2			849	0.618	0.3012	Yes
32	CSTF1	CSTF1 Entrez, Source	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa	867	0.604	0.3073	Yes
33	RBMX	RBMX Entrez, Source	RNA binding motif protein, X-linked	872	0.603	0.3173	Yes
34	CDC40	CDC40 Entrez, Source	cell division cycle 40 homolog (S. cerevisiae)	874	0.602	0.3282	Yes
35	HNRNPA0			889	0.589	0.3349	Yes
36	SF3A3	SF3A3 Entrez, Source	splicing factor 3a, subunit 3, 60kDa	899	0.582	0.3430	Yes
37	HNRNPA2B1			900	0.581	0.3539	Yes
38	CPSF7			902	0.579	0.3643	Yes
39	SF3B4	SF3B4 Entrez, Source	splicing factor 3b, subunit 4, 49kDa	912	0.569	0.3722	Yes
40	HNRNPA3			937	0.558	0.3753	Yes
41	CPSF2	CPSF2 Entrez, Source	cleavage and polyadenylation specific factor 2, 100kDa	947	0.555	0.3829	Yes
42	DNAJC8	DNAJC8 Entrez, Source	DnaJ (Hsp40) homolog, subfamily C, member 8	948	0.555	0.3933	Yes
43	NUDT21	NUDT21 Entrez, Source	nudix (nucleoside diphosphate linked moiety X)-type motif 21	970	0.539	0.3969	Yes
44	SRSF11			986	0.531	0.4022	Yes
45	SF3B3	SF3B3 Entrez, Source	splicing factor 3b, subunit 3, 130kDa	1011	0.518	0.4046	Yes
46	POLR2D	POLR2D Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide D	1035	0.507	0.4071	Yes
47	SRSF7			1039	0.503	0.4156	Yes
48	CCAR1	CCAR1 Entrez, Source	cell division cycle and apoptosis regulator 1	1044	0.497	0.4236	Yes
49	DHX38	DHX38 Entrez, Source	DEAH (Asp-Glu-Ala-His) box polypeptide 38	1048	0.496	0.4319	Yes
50	HNRNPM			1065	0.487	0.4361	Yes
51	PTBP1	PTBP1 Entrez, Source	polypyrimidine tract binding protein 1	1078	0.480	0.4415	Yes
52	CSTF2	CSTF2 Entrez, Source	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa	1088	0.469	0.4475	Yes
53	RBM8A	RBM8A Entrez, Source	RNA binding motif protein 8A	1126	0.445	0.4445	Yes
54	SRRM1	SRRM1 Entrez, Source	serine/arginine repetitive matrix 1	1162	0.423	0.4418	Yes
55	YBX1	YBX1 Entrez, Source	Y box binding protein 1	1192	0.409	0.4406	Yes
56	PRPF4	PRPF4 Entrez, Source	PRP4 pre-mRNA processing factor 4 homolog (yeast)	1236	0.385	0.4348	Yes
57	SNRNP70			1246	0.377	0.4391	Yes
58	POLR2A	POLR2A Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	1258	0.369	0.4426	Yes
59	SF3B5	SF3B5 Entrez, Source	splicing factor 3b, subunit 5, 10kDa	1277	0.356	0.4438	Yes
60	SRSF9			1286	0.350	0.4479	Yes
61	NCBP1	NCBP1 Entrez, Source	nuclear cap binding protein subunit 1, 80kDa	1292	0.348	0.4528	Yes
62	SF3B2	SF3B2 Entrez, Source	splicing factor 3b, subunit 2, 145kDa	1321	0.330	0.4505	Yes
63	POLR2B	POLR2B Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	1331	0.322	0.4538	Yes
64	SMC1A	SMC1A Entrez, Source	structural maintenance of chromosomes 1A	1342	0.315	0.4566	Yes
65	SF3A1	SF3A1 Entrez, Source	splicing factor 3a, subunit 1, 120kDa	1346	0.312	0.4615	Yes
66	SNRNP40			1394	0.285	0.4525	No
67	POLR2E	POLR2E Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	1411	0.275	0.4528	No
68	RNPS1	RNPS1 Entrez, Source	RNA binding protein S1, serine-rich domain	1421	0.268	0.4551	No
69	SF3B14	SF3B14 Entrez, Source	-	1427	0.266	0.4585	No
70	CPSF1	CPSF1 Entrez, Source	cleavage and polyadenylation specific factor 1, 160kDa	1444	0.254	0.4584	No
71	HNRNPL			1465	0.240	0.4568	No
72	PRPF8	PRPF8 Entrez, Source	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)	1485	0.225	0.4553	No
73	U2AF2	U2AF2 Entrez, Source	U2 small nuclear RNA auxiliary factor 2	1545	0.185	0.4408	No
74	POLR2H	POLR2H Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide H	1550	0.183	0.4430	No
75	HNRNPU			1586	0.160	0.4354	No
76	SNRNP200			1616	0.140	0.4292	No
77	GTF2F2	GTF2F2 Entrez, Source	general transcription factor IIF, polypeptide 2, 30kDa	1618	0.139	0.4315	No
78	PRPF6	PRPF6 Entrez, Source	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	1655	0.117	0.4228	No
79	SF3B1	SF3B1 Entrez, Source	splicing factor 3b, subunit 1, 155kDa	1659	0.114	0.4240	No
80	POLR2L	POLR2L Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	1670	0.109	0.4230	No
81	SNRPD1	SNRPD1 Entrez, Source	small nuclear ribonucleoprotein D1 polypeptide 16kDa	1674	0.106	0.4241	No
82	POLR2K	POLR2K Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	1692	0.094	0.4207	No
83	SNRPG	SNRPG Entrez, Source	small nuclear ribonucleoprotein polypeptide G	1694	0.094	0.4221	No
84	TXNL4A	TXNL4A Entrez, Source	thioredoxin-like 4A	1762	0.052	0.4028	No
85	DDX23	DDX23 Entrez, Source	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	1768	0.049	0.4022	No
86	CLP1			1775	0.044	0.4012	No
87	PABPN1	PABPN1 Entrez, Source	poly(A) binding protein, nuclear 1	1777	0.043	0.4017	No
88	PHF5A	PHF5A Entrez, Source	PHD finger protein 5A	1875	-0.016	0.3726	No
89	CPSF3	CPSF3 Entrez, Source	cleavage and polyadenylation specific factor 3, 73kDa	1903	-0.038	0.3651	No
90	GTF2F1	GTF2F1 Entrez, Source	general transcription factor IIF, polypeptide 1, 74kDa	1920	-0.052	0.3612	No
91	NCBP2	NCBP2 Entrez, Source	nuclear cap binding protein subunit 2, 20kDa	1933	-0.062	0.3588	No
92	MAGOH	MAGOH Entrez, Source	mago-nashi homolog, proliferation-associated (Drosophila)	1973	-0.086	0.3486	No
93	UPF3B	UPF3B Entrez, Source	UPF3 regulator of nonsense transcripts homolog B (yeast)	1979	-0.089	0.3487	No
94	HNRNPUL1			2056	-0.150	0.3285	No
95	SRSF5			2080	-0.167	0.3246	No
96	SNRPD3	SNRPD3 Entrez, Source	small nuclear ribonucleoprotein D3 polypeptide 18kDa	2090	-0.174	0.3252	No
97	EFTUD2	EFTUD2 Entrez, Source	elongation factor Tu GTP binding domain containing 2	2183	-0.235	0.3017	No
98	SNRPE	SNRPE Entrez, Source	small nuclear ribonucleoprotein polypeptide E	2256	-0.284	0.2851	No
99	SNRPD2	SNRPD2 Entrez, Source	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	2407	-0.379	0.2467	No
100	NHP2L1	NHP2L1 Entrez, Source	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)	2770	-0.694	0.1500	No
101	HNRNPC			2988	-0.959	0.1021	No
102	LSM2	LSM2 Entrez, Source	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	3148	-1.235	0.0769	No