Details for gene set REACTOME_MRNA

Table: GSEA Results Summary

Dataset	chrom
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	REACTOME_MRNA_PROCESSING
Enrichment Score (ES)	0.40888074
Normalized Enrichment Score (NES)	1.7786515
Nominal p-value	0.0
FDR q-value	0.02660942
FWER p-Value	0.25

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PCF11	PCF11 Entrez, Source	PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)	66	2.239	0.0105	Yes
2	SNRPF	SNRPF Entrez, Source	small nuclear ribonucleoprotein polypeptide F	110	2.029	0.0252	Yes
3	RNGTT	RNGTT Entrez, Source	RNA guanylyltransferase and 5'-phosphatase	122	1.910	0.0481	Yes
4	PAPOLA	PAPOLA Entrez, Source	poly(A) polymerase alpha	246	1.396	0.0296	Yes
5	MNAT1	MNAT1 Entrez, Source	menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)	247	1.393	0.0487	Yes
6	POLR2G	POLR2G Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide G	268	1.353	0.0612	Yes
7	FUS	FUS Entrez, Source	fusion (involved in t(12;16) in malignant liposarcoma)	323	1.218	0.0614	Yes
8	PCBP1	PCBP1 Entrez, Source	poly(rC) binding protein 1	338	1.186	0.0734	Yes
9	PCBP2	PCBP2 Entrez, Source	poly(rC) binding protein 2	361	1.144	0.0824	Yes
10	NUP50	NUP50 Entrez, Source	nucleoporin 50kDa	383	1.108	0.0912	Yes
11	POLR2I	POLR2I Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa	391	1.097	0.1041	Yes
12	CD2BP2	CD2BP2 Entrez, Source	CD2 (cytoplasmic tail) binding protein 2	406	1.076	0.1146	Yes
13	HNRNPD			431	1.023	0.1213	Yes
14	SRSF1			475	0.974	0.1215	Yes
15	SUPT5H	SUPT5H Entrez, Source	suppressor of Ty 5 homolog (S. cerevisiae)	485	0.960	0.1319	Yes
16	SNRPA1	SNRPA1 Entrez, Source	small nuclear ribonucleoprotein polypeptide A'	509	0.933	0.1377	Yes
17	RBM5	RBM5 Entrez, Source	RNA binding motif protein 5	514	0.928	0.1493	Yes
18	HNRNPA1			565	0.876	0.1460	Yes
19	HNRNPF			612	0.828	0.1432	Yes
20	POLR2C	POLR2C Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	629	0.809	0.1495	Yes
21	HNRNPK			639	0.802	0.1577	Yes
22	RAE1	RAE1 Entrez, Source	RAE1 RNA export 1 homolog (S. pombe)	646	0.792	0.1668	Yes
23	U2AF1	U2AF1 Entrez, Source	U2 small nuclear RNA auxiliary factor 1	677	0.762	0.1680	Yes
24	POLR2F	POLR2F Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide F	681	0.759	0.1776	Yes
25	CSTF3	CSTF3 Entrez, Source	cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa	698	0.741	0.1828	Yes
26	HNRNPH1			699	0.741	0.1930	Yes
27	HNRNPR			712	0.728	0.1993	Yes
28	SRSF4			723	0.718	0.2061	Yes
29	SRSF6			740	0.703	0.2109	Yes
30	SNRPB2	SNRPB2 Entrez, Source	small nuclear ribonucleoprotein polypeptide B''	756	0.687	0.2157	Yes
31	ADARB1	ADARB1 Entrez, Source	adenosine deaminase, RNA-specific, B1 (RED1 homolog rat)	794	0.659	0.2135	Yes
32	SF3A2	SF3A2 Entrez, Source	splicing factor 3a, subunit 2, 66kDa	812	0.644	0.2171	Yes
33	SRSF2			836	0.628	0.2187	Yes
34	DHX9	DHX9 Entrez, Source	DEAH (Asp-Glu-Ala-His) box polypeptide 9	837	0.628	0.2273	Yes
35	SUGP1			844	0.619	0.2340	Yes
36	SNRPA	SNRPA Entrez, Source	small nuclear ribonucleoprotein polypeptide A	846	0.618	0.2422	Yes
37	HNRNPH2			849	0.618	0.2500	Yes
38	CSTF1	CSTF1 Entrez, Source	cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa	867	0.604	0.2531	Yes
39	RBMX	RBMX Entrez, Source	RNA binding motif protein, X-linked	872	0.603	0.2602	Yes
40	CDC40	CDC40 Entrez, Source	cell division cycle 40 homolog (S. cerevisiae)	874	0.602	0.2682	Yes
41	CDK7	CDK7 Entrez, Source	cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)	879	0.597	0.2751	Yes
42	HNRNPA0			889	0.589	0.2805	Yes
43	SF3A3	SF3A3 Entrez, Source	splicing factor 3a, subunit 3, 60kDa	899	0.582	0.2857	Yes
44	HNRNPA2B1			900	0.581	0.2937	Yes
45	CPSF7			902	0.579	0.3013	Yes
46	NUPL1	NUPL1 Entrez, Source	nucleoporin like 1	907	0.577	0.3081	Yes
47	SF3B4	SF3B4 Entrez, Source	splicing factor 3b, subunit 4, 49kDa	912	0.569	0.3146	Yes
48	HNRNPA3			937	0.558	0.3150	Yes
49	CPSF2	CPSF2 Entrez, Source	cleavage and polyadenylation specific factor 2, 100kDa	947	0.555	0.3198	Yes
50	DNAJC8	DNAJC8 Entrez, Source	DnaJ (Hsp40) homolog, subfamily C, member 8	948	0.555	0.3274	Yes
51	NUDT21	NUDT21 Entrez, Source	nudix (nucleoside diphosphate linked moiety X)-type motif 21	970	0.539	0.3284	Yes
52	SRSF11			986	0.531	0.3311	Yes
53	SF3B3	SF3B3 Entrez, Source	splicing factor 3b, subunit 3, 130kDa	1011	0.518	0.3309	Yes
54	POLR2D	POLR2D Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide D	1035	0.507	0.3308	Yes
55	SRSF7			1039	0.503	0.3368	Yes
56	CCAR1	CCAR1 Entrez, Source	cell division cycle and apoptosis regulator 1	1044	0.497	0.3424	Yes
57	AAAS	AAAS Entrez, Source	achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)	1047	0.496	0.3486	Yes
58	DHX38	DHX38 Entrez, Source	DEAH (Asp-Glu-Ala-His) box polypeptide 38	1048	0.496	0.3554	Yes
59	HNRNPM			1065	0.487	0.3572	Yes
60	PTBP1	PTBP1 Entrez, Source	polypyrimidine tract binding protein 1	1078	0.480	0.3601	Yes
61	CSTF2	CSTF2 Entrez, Source	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa	1088	0.469	0.3638	Yes
62	NUP37	NUP37 Entrez, Source	nucleoporin 37kDa	1102	0.460	0.3661	Yes
63	RBM8A	RBM8A Entrez, Source	RNA binding motif protein 8A	1126	0.445	0.3652	Yes
64	NUP88	NUP88 Entrez, Source	nucleoporin 88kDa	1129	0.444	0.3707	Yes
65	ADAR	ADAR Entrez, Source	adenosine deaminase, RNA-specific	1155	0.427	0.3689	Yes
66	SRRM1	SRRM1 Entrez, Source	serine/arginine repetitive matrix 1	1162	0.423	0.3729	Yes
67	NUP85	NUP85 Entrez, Source	nucleoporin 85kDa	1175	0.416	0.3749	Yes
68	YBX1	YBX1 Entrez, Source	Y box binding protein 1	1192	0.409	0.3756	Yes
69	NUP133	NUP133 Entrez, Source	nucleoporin 133kDa	1203	0.404	0.3781	Yes
70	NUP214	NUP214 Entrez, Source	nucleoporin 214kDa	1209	0.403	0.3821	Yes
71	PRPF4	PRPF4 Entrez, Source	PRP4 pre-mRNA processing factor 4 homolog (yeast)	1236	0.385	0.3794	Yes
72	SNRNP70			1246	0.377	0.3819	Yes
73	POLR2A	POLR2A Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	1258	0.369	0.3836	Yes
74	NUP93	NUP93 Entrez, Source	nucleoporin 93kDa	1268	0.362	0.3858	Yes
75	NUP188	NUP188 Entrez, Source	nucleoporin 188kDa	1273	0.360	0.3895	Yes
76	SF3B5	SF3B5 Entrez, Source	splicing factor 3b, subunit 5, 10kDa	1277	0.356	0.3935	Yes
77	SRSF9			1286	0.350	0.3958	Yes
78	NCBP1	NCBP1 Entrez, Source	nuclear cap binding protein subunit 1, 80kDa	1292	0.348	0.3991	Yes
79	NUP205	NUP205 Entrez, Source	nucleoporin 205kDa	1320	0.330	0.3953	Yes
80	SF3B2	SF3B2 Entrez, Source	splicing factor 3b, subunit 2, 145kDa	1321	0.330	0.3999	Yes
81	POLR2B	POLR2B Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	1331	0.322	0.4015	Yes
82	SMC1A	SMC1A Entrez, Source	structural maintenance of chromosomes 1A	1342	0.315	0.4028	Yes
83	SF3A1	SF3A1 Entrez, Source	splicing factor 3a, subunit 1, 120kDa	1346	0.312	0.4062	Yes
84	NUP107	NUP107 Entrez, Source	nucleoporin 107kDa	1352	0.310	0.4089	Yes
85	SNRNP40			1394	0.285	0.4002	No
86	POLR2E	POLR2E Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa	1411	0.275	0.3991	No
87	RNPS1	RNPS1 Entrez, Source	RNA binding protein S1, serine-rich domain	1421	0.268	0.4000	No
88	SF3B14	SF3B14 Entrez, Source	-	1427	0.266	0.4022	No
89	NUP155	NUP155 Entrez, Source	nucleoporin 155kDa	1438	0.259	0.4026	No
90	CPSF1	CPSF1 Entrez, Source	cleavage and polyadenylation specific factor 1, 160kDa	1444	0.254	0.4046	No
91	HNRNPL			1465	0.240	0.4018	No
92	NUP54	NUP54 Entrez, Source	nucleoporin 54kDa	1480	0.228	0.4006	No
93	PRPF8	PRPF8 Entrez, Source	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)	1485	0.225	0.4025	No
94	SEH1L	SEH1L Entrez, Source	SEH1-like (S. cerevisiae)	1507	0.207	0.3989	No
95	CCNH	CCNH Entrez, Source	cyclin H	1539	0.187	0.3920	No
96	NXF1	NXF1 Entrez, Source	nuclear RNA export factor 1	1542	0.187	0.3939	No
97	U2AF2	U2AF2 Entrez, Source	U2 small nuclear RNA auxiliary factor 2	1545	0.185	0.3958	No
98	POLR2H	POLR2H Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide H	1550	0.183	0.3971	No
99	NUP62	NUP62 Entrez, Source	nucleoporin 62kDa	1575	0.166	0.3920	No
100	HNRNPU			1586	0.160	0.3912	No
101	SNRNP200			1616	0.140	0.3842	No
102	GTF2F2	GTF2F2 Entrez, Source	general transcription factor IIF, polypeptide 2, 30kDa	1618	0.139	0.3858	No
103	PRPF6	PRPF6 Entrez, Source	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	1655	0.117	0.3764	No
104	SF3B1	SF3B1 Entrez, Source	splicing factor 3b, subunit 1, 155kDa	1659	0.114	0.3770	No
105	POLR2L	POLR2L Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	1670	0.109	0.3755	No
106	SNRPD1	SNRPD1 Entrez, Source	small nuclear ribonucleoprotein D1 polypeptide 16kDa	1674	0.106	0.3760	No
107	POLR2K	POLR2K Entrez, Source	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	1692	0.094	0.3721	No
108	SNRPG	SNRPG Entrez, Source	small nuclear ribonucleoprotein polypeptide G	1694	0.094	0.3731	No
109	NUPL2	NUPL2 Entrez, Source	nucleoporin like 2	1697	0.093	0.3737	No
110	TPR	TPR Entrez, Source	translocated promoter region (to activated MET oncogene)	1726	0.075	0.3662	No
111	TXNL4A	TXNL4A Entrez, Source	thioredoxin-like 4A	1762	0.052	0.3562	No
112	DDX23	DDX23 Entrez, Source	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	1768	0.049	0.3553	No
113	CLP1			1775	0.044	0.3541	No
114	PABPN1	PABPN1 Entrez, Source	poly(A) binding protein, nuclear 1	1777	0.043	0.3543	No
115	PHF5A	PHF5A Entrez, Source	PHD finger protein 5A	1875	-0.016	0.3248	No
116	CPSF3	CPSF3 Entrez, Source	cleavage and polyadenylation specific factor 3, 73kDa	1903	-0.038	0.3171	No
117	GTF2F1	GTF2F1 Entrez, Source	general transcription factor IIF, polypeptide 1, 74kDa	1920	-0.052	0.3129	No
118	NCBP2	NCBP2 Entrez, Source	nuclear cap binding protein subunit 2, 20kDa	1933	-0.062	0.3100	No
119	ERCC3	ERCC3 Entrez, Source	excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)	1944	-0.069	0.3079	No
120	EIF4E	EIF4E Entrez, Source	eukaryotic translation initiation factor 4E	1971	-0.086	0.3011	No
121	MAGOH	MAGOH Entrez, Source	mago-nashi homolog, proliferation-associated (Drosophila)	1973	-0.086	0.3020	No
122	UPF3B	UPF3B Entrez, Source	UPF3 regulator of nonsense transcripts homolog B (yeast)	1979	-0.089	0.3017	No
123	NUP43	NUP43 Entrez, Source	nucleoporin 43kDa	1986	-0.096	0.3012	No
124	GTF2H4	GTF2H4 Entrez, Source	general transcription factor IIH, polypeptide 4, 52kDa	2025	-0.126	0.2912	No
125	HNRNPUL1			2056	-0.150	0.2841	No
126	SRSF5			2080	-0.167	0.2794	No
127	SNRPD3	SNRPD3 Entrez, Source	small nuclear ribonucleoprotein D3 polypeptide 18kDa	2090	-0.174	0.2790	No
128	EFTUD2	EFTUD2 Entrez, Source	elongation factor Tu GTP binding domain containing 2	2183	-0.235	0.2540	No
129	GTF2H3	GTF2H3 Entrez, Source	general transcription factor IIH, polypeptide 3, 34kDa	2204	-0.248	0.2513	No
130	ERCC2	ERCC2 Entrez, Source	excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D)	2224	-0.262	0.2491	No
131	SNRPE	SNRPE Entrez, Source	small nuclear ribonucleoprotein polypeptide E	2256	-0.284	0.2435	No
132	SNRPD2	SNRPD2 Entrez, Source	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	2407	-0.379	0.2027	No
133	RNMT	RNMT Entrez, Source	RNA (guanine-7-) methyltransferase	2471	-0.439	0.1894	No
134	METTL3	METTL3 Entrez, Source	methyltransferase like 3	2488	-0.452	0.1907	No
135	NUP153	NUP153 Entrez, Source	nucleoporin 153kDa	2537	-0.489	0.1827	No
136	RANBP2	RANBP2 Entrez, Source	RAN binding protein 2	2542	-0.493	0.1883	No
137	NUP210	NUP210 Entrez, Source	nucleoporin 210kDa	2747	-0.665	0.1348	No
138	NHP2L1	NHP2L1 Entrez, Source	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)	2770	-0.694	0.1376	No
139	NUP35	NUP35 Entrez, Source	nucleoporin 35kDa	2894	-0.835	0.1114	No
140	HNRNPC			2988	-0.959	0.0960	No
141	GTF2H1	GTF2H1 Entrez, Source	general transcription factor IIH, polypeptide 1, 62kDa	2994	-0.969	0.1078	No
142	LSM2	LSM2 Entrez, Source	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	3148	-1.235	0.0779	No