Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | chrom |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | REACTOME_MRNA_3_END_PROCESSING |
| Enrichment Score (ES) | 0.5446546 |
| Normalized Enrichment Score (NES) | 1.7702634 |
| Nominal p-value | 0.005172414 |
| FDR q-value | 0.023609282 |
| FWER p-Value | 0.269 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PCF11 | PCF11 Entrez, Source | PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae) | 66 | 2.239 | 0.1218 | Yes |
| 2 | PAPOLA | PAPOLA Entrez, Source | poly(A) polymerase alpha | 246 | 1.396 | 0.1568 | Yes |
| 3 | SRSF1 | 475 | 0.974 | 0.1507 | Yes | ||
| 4 | U2AF1 | U2AF1 Entrez, Source | U2 small nuclear RNA auxiliary factor 1 | 677 | 0.762 | 0.1392 | Yes |
| 5 | CSTF3 | CSTF3 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | 698 | 0.741 | 0.1800 | Yes |
| 6 | SRSF4 | 723 | 0.718 | 0.2182 | Yes | ||
| 7 | SRSF6 | 740 | 0.703 | 0.2578 | Yes | ||
| 8 | SRSF2 | 836 | 0.628 | 0.2693 | Yes | ||
| 9 | CSTF1 | CSTF1 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 867 | 0.604 | 0.2986 | Yes |
| 10 | CDC40 | CDC40 Entrez, Source | cell division cycle 40 homolog (S. cerevisiae) | 874 | 0.602 | 0.3348 | Yes |
| 11 | CPSF7 | 902 | 0.579 | 0.3633 | Yes | ||
| 12 | CPSF2 | CPSF2 Entrez, Source | cleavage and polyadenylation specific factor 2, 100kDa | 947 | 0.555 | 0.3853 | Yes |
| 13 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 970 | 0.539 | 0.4128 | Yes |
| 14 | SRSF11 | 986 | 0.531 | 0.4418 | Yes | ||
| 15 | SRSF7 | 1039 | 0.503 | 0.4582 | Yes | ||
| 16 | DHX38 | DHX38 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 38 | 1048 | 0.496 | 0.4871 | Yes |
| 17 | CSTF2 | CSTF2 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa | 1088 | 0.469 | 0.5052 | Yes |
| 18 | RBM8A | RBM8A Entrez, Source | RNA binding motif protein 8A | 1126 | 0.445 | 0.5223 | Yes |
| 19 | SRRM1 | SRRM1 Entrez, Source | serine/arginine repetitive matrix 1 | 1162 | 0.423 | 0.5386 | Yes |
| 20 | SRSF9 | 1286 | 0.350 | 0.5242 | Yes | ||
| 21 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 1292 | 0.348 | 0.5447 | Yes |
| 22 | RNPS1 | RNPS1 Entrez, Source | RNA binding protein S1, serine-rich domain | 1421 | 0.268 | 0.5236 | No |
| 23 | CPSF1 | CPSF1 Entrez, Source | cleavage and polyadenylation specific factor 1, 160kDa | 1444 | 0.254 | 0.5332 | No |
| 24 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 1545 | 0.185 | 0.5152 | No |
| 25 | CLP1 | 1775 | 0.044 | 0.4500 | No | ||
| 26 | PABPN1 | PABPN1 Entrez, Source | poly(A) binding protein, nuclear 1 | 1777 | 0.043 | 0.4524 | No |
| 27 | CPSF3 | CPSF3 Entrez, Source | cleavage and polyadenylation specific factor 3, 73kDa | 1903 | -0.038 | 0.4178 | No |
| 28 | NCBP2 | NCBP2 Entrez, Source | nuclear cap binding protein subunit 2, 20kDa | 1933 | -0.062 | 0.4131 | No |
| 29 | MAGOH | MAGOH Entrez, Source | mago-nashi homolog, proliferation-associated (Drosophila) | 1973 | -0.086 | 0.4070 | No |
| 30 | UPF3B | UPF3B Entrez, Source | UPF3 regulator of nonsense transcripts homolog B (yeast) | 1979 | -0.089 | 0.4111 | No |
| 31 | SRSF5 | 2080 | -0.167 | 0.3921 | No |
