Datasetchrom
PhenotypeNoPhenotypeAvailable
Upregulated in classna_neg
GeneSetREACTOME_MITOCHONDRIAL_PROTEIN_IMPORT
Enrichment Score (ES)-0.5283108
Normalized Enrichment Score (NES)-1.9281137
Nominal p-value0.0024875621
FDR q-value0.0030296922
FWER p-Value0.054
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1TOMM20TOMM20
Entrez,  Source
translocase of outer mitochondrial membrane 20 homolog (yeast)4780.972-0.1043No
2PMPCAPMPCA
Entrez,  Source
peptidase (mitochondrial processing) alpha8570.613-0.1928No
3TIMM17ATIMM17A
Entrez,  Source
translocase of inner mitochondrial membrane 17 homolog A (yeast)8640.607-0.1710No
4CYC1CYC1
Entrez,  Source
cytochrome c-19430.556-0.1726No
5TIMM8BTIMM8B
Entrez,  Source
translocase of inner mitochondrial membrane 8 homolog B (yeast)11070.458-0.2032No
6ATP5BATP5B
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide13960.283-0.2778No
7HSPD1HSPD1
Entrez,  Source
heat shock 60kDa protein 1 (chaperonin)15160.200-0.3054No
8ATP5A1ATP5A1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle15260.193-0.3005No
9TIMM13TIMM13
Entrez,  Source
translocase of inner mitochondrial membrane 13 homolog (yeast)15630.174-0.3045No
10SLC25A13SLC25A13
Entrez,  Source
solute carrier family 25, member 13 (citrin)16480.120-0.3248No
11MTX1MTX1
Entrez,  Source
metaxin 12249-0.278-0.4922No
12HSPA92277-0.295-0.4888No
13VDAC1VDAC1
Entrez,  Source
voltage-dependent anion channel 12411-0.383-0.5135Yes
14CSCS
Entrez,  Source
citrate synthase2430-0.400-0.5033Yes
15TOMM70ATOMM70A
Entrez,  Source
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)2450-0.417-0.4927Yes
16TIMM50TIMM50
Entrez,  Source
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)2494-0.455-0.4879Yes
17TIMM8ATIMM8A
Entrez,  Source
translocase of inner mitochondrial membrane 8 homolog A (yeast)2500-0.457-0.4716Yes
18SLC25A6SLC25A6
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 62570-0.516-0.4721Yes
19BCS1LBCS1L
Entrez,  Source
BCS1-like (yeast)2607-0.546-0.4616Yes
20MTX2MTX2
Entrez,  Source
metaxin 22619-0.560-0.4431Yes
21GRPEL1GRPEL1
Entrez,  Source
GrpE-like 1, mitochondrial (E. coli)2664-0.597-0.4330Yes
22SLC25A12SLC25A12
Entrez,  Source
solute carrier family 25 (mitochondrial carrier, Aralar), member 122705-0.626-0.4206Yes
23TIMM44TIMM44
Entrez,  Source
translocase of inner mitochondrial membrane 44 homolog (yeast)2798-0.730-0.4197Yes
24SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 42831-0.772-0.3992Yes
25ACO2ACO2
Entrez,  Source
aconitase 2, mitochondrial2852-0.794-0.3743Yes
26TOMM22TOMM22
Entrez,  Source
translocase of outer mitochondrial membrane 22 homolog (yeast)2867-0.809-0.3471Yes
27TOMM40TOMM40
Entrez,  Source
translocase of outer mitochondrial membrane 40 homolog (yeast)2940-0.885-0.3342Yes
28SAMM50SAMM50
Entrez,  Source
sorting and assembly machinery component 50 homolog (S. cerevisiae)2945-0.893-0.3007Yes
29CHCHD4CHCHD4
Entrez,  Source
coiled-coil-helix-coiled-coil-helix domain containing 42959-0.910-0.2693Yes
30TOMM52977-0.941-0.2378Yes
31TIMM17BTIMM17B
Entrez,  Source
translocase of inner mitochondrial membrane 17 homolog B (yeast)3035-1.044-0.2142Yes
32TIMM9TIMM9
Entrez,  Source
translocase of inner mitochondrial membrane 9 homolog (yeast)3221-1.407-0.2146Yes
33TIMM10TIMM10
Entrez,  Source
translocase of inner mitochondrial membrane 10 homolog (yeast)3224-1.410-0.1605Yes
34PAM163313-1.720-0.1199Yes
35DNAJC19DNAJC19
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily C, member 193331-1.853-0.0531Yes
36TIMM22TIMM22
Entrez,  Source
translocase of inner mitochondrial membrane 22 homolog (yeast)3339-1.9040.0187Yes
Table: GSEA details [plain text format]



Fig 2: REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT: Random ES distribution   
Gene set null distribution of ES for REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT