Datasetchrom
PhenotypeNoPhenotypeAvailable
Upregulated in classna_neg
GeneSetREACTOME_INFLUENZA_LIFE_CYCLE
Enrichment Score (ES)-0.43949515
Normalized Enrichment Score (NES)-2.056843
Nominal p-value0.0
FDR q-value6.9705385E-4
FWER p-Value0.011
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_INFLUENZA_LIFE_CYCLE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1GRSF1GRSF1
Entrez,  Source
G-rich RNA sequence binding factor 11171.965-0.0115No
2CLTACLTA
Entrez,  Source
clathrin, light chain (Lca)1661.626-0.0061No
3POLR2GPOLR2G
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide G2681.353-0.0203No
4NUP50NUP50
Entrez,  Source
nucleoporin 50kDa3831.108-0.0414No
5POLR2IPOLR2I
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa3911.097-0.0300No
6CALRCALR
Entrez,  Source
calreticulin4680.984-0.0411No
7POLR2CPOLR2C
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa6290.809-0.0799No
8RAE1RAE1
Entrez,  Source
RAE1 RNA export 1 homolog (S. pombe)6460.792-0.0751No
9RANRAN
Entrez,  Source
RAN, member RAS oncogene family6670.770-0.0717No
10POLR2FPOLR2F
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide F6810.759-0.0663No
11NUPL1NUPL1
Entrez,  Source
nucleoporin like 19070.577-0.1278No
12RPL13RPL13
Entrez,  Source
ribosomal protein L1310210.511-0.1560No
13POLR2DPOLR2D
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide D10350.507-0.1537No
14AAASAAAS
Entrez,  Source
achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)10470.496-0.1509No
15NUP37NUP37
Entrez,  Source
nucleoporin 37kDa11020.460-0.1617No
16NUP88NUP88
Entrez,  Source
nucleoporin 88kDa11290.444-0.1642No
17NUP85NUP85
Entrez,  Source
nucleoporin 85kDa11750.416-0.1728No
18NUP133NUP133
Entrez,  Source
nucleoporin 133kDa12030.404-0.1761No
19NUP214NUP214
Entrez,  Source
nucleoporin 214kDa12090.403-0.1726No
20POLR2APOLR2A
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa12580.369-0.1827No
21NUP93NUP93
Entrez,  Source
nucleoporin 93kDa12680.362-0.1810No
22NUP188NUP188
Entrez,  Source
nucleoporin 188kDa12730.360-0.1778No
23RPL32RPL32
Entrez,  Source
ribosomal protein L3212990.345-0.1812No
24CANXCANX
Entrez,  Source
calnexin13040.342-0.1782No
25NUP205NUP205
Entrez,  Source
nucleoporin 205kDa13200.330-0.1787No
26POLR2BPOLR2B
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa13310.322-0.1778No
27NUP107NUP107
Entrez,  Source
nucleoporin 107kDa13520.310-0.1801No
28XPO1XPO1
Entrez,  Source
exportin 1 (CRM1 homolog, yeast)14040.278-0.1922No
29POLR2EPOLR2E
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa14110.275-0.1906No
30NUP155NUP155
Entrez,  Source
nucleoporin 155kDa14380.259-0.1954No
31NUP54NUP54
Entrez,  Source
nucleoporin 54kDa14800.228-0.2051No
32SEH1LSEH1L
Entrez,  Source
SEH1-like (S. cerevisiae)15070.207-0.2104No
33HSP90AA1HSP90AA1
Entrez,  Source
heat shock protein 90kDa alpha (cytosolic), class A member 115310.190-0.2151No
34POLR2HPOLR2H
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide H15500.183-0.2184No
35NUP62NUP62
Entrez,  Source
nucleoporin 62kDa15750.166-0.2236No
36RPL26L1RPL26L1
Entrez,  Source
ribosomal protein L26-like 116070.147-0.2313No
37KPNA1KPNA1
Entrez,  Source
karyopherin alpha 1 (importin alpha 5)16080.147-0.2295No
38GTF2F2GTF2F2
Entrez,  Source
general transcription factor IIF, polypeptide 2, 30kDa16180.139-0.2305No
39POLR2LPOLR2L
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa16700.109-0.2447No
40POLR2KPOLR2K
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa16920.094-0.2499No
41NUPL2NUPL2
Entrez,  Source
nucleoporin like 216970.093-0.2500No
42TPRTPR
Entrez,  Source
translocated promoter region (to activated MET oncogene)17260.075-0.2576No
43RPS27ARPS27A
Entrez,  Source
ribosomal protein S27a17390.066-0.2605No
44IPO517780.042-0.2715No
45RPL12RPL12
Entrez,  Source
ribosomal protein L1217850.038-0.2729No
46KPNB1KPNB1
Entrez,  Source
karyopherin (importin) beta 11902-0.037-0.3078No
47GTF2F1GTF2F1
Entrez,  Source
general transcription factor IIF, polypeptide 1, 74kDa1920-0.052-0.3123No
48RPL15RPL15
Entrez,  Source
ribosomal protein L151943-0.068-0.3182No
49RPL10ARPL10A
Entrez,  Source
ribosomal protein L10a1954-0.075-0.3203No
50NUP43NUP43
Entrez,  Source
nucleoporin 43kDa1986-0.096-0.3286No
51RPL18RPL18
Entrez,  Source
ribosomal protein L182012-0.114-0.3348No
52CLTCCLTC
Entrez,  Source
clathrin, heavy chain (Hc)2121-0.198-0.3653No
53DNAJC3DNAJC3
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily C, member 32206-0.250-0.3878No
54RPS24RPS24
Entrez,  Source
ribosomal protein S242211-0.253-0.3859No
55RPL5RPL5
Entrez,  Source
ribosomal protein L52234-0.269-0.3893No
56RPL28RPL28
Entrez,  Source
ribosomal protein L282309-0.310-0.4081No
57RPL11RPL11
Entrez,  Source
ribosomal protein L112370-0.350-0.4221No
58RPL23ARPL23A
Entrez,  Source
ribosomal protein L23a2397-0.373-0.4254No
59RPL7ARPL7A
Entrez,  Source
ribosomal protein L7a2402-0.376-0.4220No
60RPL13ARPL13A
Entrez,  Source
ribosomal protein L13a2427-0.399-0.4244No
61RPL29RPL29
Entrez,  Source
ribosomal protein L292466-0.433-0.4307No
62RPL21RPL21
Entrez,  Source
ribosomal protein L212496-0.455-0.4339Yes
63RPL8RPL8
Entrez,  Source
ribosomal protein L82503-0.460-0.4301Yes
64RPL27RPL27
Entrez,  Source
ribosomal protein L272512-0.469-0.4267Yes
65RPL14RPL14
Entrez,  Source
ribosomal protein L142534-0.488-0.4271Yes
66NUP153NUP153
Entrez,  Source
nucleoporin 153kDa2537-0.489-0.4217Yes
67RANBP2RANBP2
Entrez,  Source
RAN binding protein 22542-0.493-0.4169Yes
68RPL6RPL6
Entrez,  Source
ribosomal protein L62569-0.516-0.4185Yes
69RPL17RPL17
Entrez,  Source
ribosomal protein L172574-0.518-0.4133Yes
70RPL18ARPL18A
Entrez,  Source
ribosomal protein L18a2598-0.538-0.4137Yes
71RPL4RPL4
Entrez,  Source
ribosomal protein L42632-0.572-0.4167Yes
72RPL27ARPL27A
Entrez,  Source
ribosomal protein L27a2635-0.574-0.4103Yes
73RPS8RPS8
Entrez,  Source
ribosomal protein S82658-0.592-0.4097Yes
74RPL35RPL35
Entrez,  Source
ribosomal protein L352691-0.615-0.4119Yes
75NUP210NUP210
Entrez,  Source
nucleoporin 210kDa2747-0.665-0.4205Yes
76RPL9RPL9
Entrez,  Source
ribosomal protein L92754-0.671-0.4141Yes
77RPL7RPL7
Entrez,  Source
ribosomal protein L72766-0.684-0.4090Yes
78RPS15RPS15
Entrez,  Source
ribosomal protein S152780-0.712-0.4042Yes
79RPS7RPS7
Entrez,  Source
ribosomal protein S72811-0.746-0.4042Yes
80RPS5RPS5
Entrez,  Source
ribosomal protein S52832-0.773-0.4008Yes
81RPL30RPL30
Entrez,  Source
ribosomal protein L302838-0.780-0.3927Yes
82RPSARPSA
Entrez,  Source
ribosomal protein SA2843-0.783-0.3843Yes
83RPS3ARPS3A
Entrez,  Source
ribosomal protein S3A2847-0.786-0.3756Yes
84RPL24RPL24
Entrez,  Source
ribosomal protein L242863-0.805-0.3702Yes
85RPL34RPL34
Entrez,  Source
ribosomal protein L342865-0.809-0.3606Yes
86RPL23RPL23
Entrez,  Source
ribosomal protein L232891-0.831-0.3580Yes
87NUP35NUP35
Entrez,  Source
nucleoporin 35kDa2894-0.835-0.3483Yes
88RPL35ARPL35A
Entrez,  Source
ribosomal protein L35a2898-0.838-0.3389Yes
89RPL3RPL3
Entrez,  Source
ribosomal protein L32902-0.843-0.3295Yes
90RPLP0RPLP0
Entrez,  Source
ribosomal protein, large, P02912-0.858-0.3217Yes
91RPL36RPL36
Entrez,  Source
ribosomal protein L362920-0.867-0.3132Yes
92RPS13RPS13
Entrez,  Source
ribosomal protein S132928-0.875-0.3045Yes
93RPS9RPS9
Entrez,  Source
ribosomal protein S92930-0.876-0.2941Yes
94RPL22RPL22
Entrez,  Source
ribosomal protein L222942-0.889-0.2865Yes
95RPS10RPS10
Entrez,  Source
ribosomal protein S102958-0.909-0.2799Yes
96RPL10RPL10
Entrez,  Source
ribosomal protein L102961-0.912-0.2693Yes
97RPL31RPL31
Entrez,  Source
ribosomal protein L312965-0.916-0.2589Yes
98RPS25RPS25
Entrez,  Source
ribosomal protein S252976-0.938-0.2504Yes
99RPS29RPS29
Entrez,  Source
ribosomal protein S292989-0.964-0.2422Yes
100RPS6RPS6
Entrez,  Source
ribosomal protein S62990-0.965-0.2304Yes
101RPS3RPS3
Entrez,  Source
ribosomal protein S32992-0.968-0.2188Yes
102RPS11RPS11
Entrez,  Source
ribosomal protein S112996-0.971-0.2077Yes
103RPS14RPS14
Entrez,  Source
ribosomal protein S143010-0.996-0.1994Yes
104FAUFAU
Entrez,  Source
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S303011-0.998-0.1872Yes
105RPS23RPS23
Entrez,  Source
ribosomal protein S233028-1.022-0.1795Yes
106RPL38RPL38
Entrez,  Source
ribosomal protein L383041-1.055-0.1702Yes
107RPS18RPS18
Entrez,  Source
ribosomal protein S183053-1.078-0.1602Yes
108RPS16RPS16
Entrez,  Source
ribosomal protein S163066-1.097-0.1504Yes
109RPS2RPS2
Entrez,  Source
ribosomal protein S23076-1.109-0.1395Yes
110RPS19RPS19
Entrez,  Source
ribosomal protein S193083-1.121-0.1276Yes
111RPL37ARPL37A
Entrez,  Source
ribosomal protein L37a3088-1.125-0.1149Yes
112RPS4XRPS4X
Entrez,  Source
ribosomal protein S4, X-linked3097-1.137-0.1034Yes
113RPS21RPS21
Entrez,  Source
ribosomal protein S213111-1.163-0.0931Yes
114RPS12RPS12
Entrez,  Source
ribosomal protein S123149-1.236-0.0891Yes
115RPS28RPS28
Entrez,  Source
ribosomal protein S283187-1.329-0.0841Yes
116RPLP2RPLP2
Entrez,  Source
ribosomal protein, large, P23209-1.380-0.0735Yes
117RPS15ARPS15A
Entrez,  Source
ribosomal protein S15a3238-1.448-0.0642Yes
118RPL19RPL19
Entrez,  Source
ribosomal protein L193243-1.476-0.0473Yes
119RPS26RPS26
Entrez,  Source
ribosomal protein S263292-1.635-0.0418Yes
120RPS20RPS20
Entrez,  Source
ribosomal protein S203295-1.644-0.0222Yes
121RPS27RPS27
Entrez,  Source
ribosomal protein S27 (metallopanstimulin 1)3354-1.987-0.0155Yes
122RPLP1RPLP1
Entrez,  Source
ribosomal protein, large, P13377-2.4230.0076Yes
Table: GSEA details [plain text format]



Fig 2: REACTOME_INFLUENZA_LIFE_CYCLE: Random ES distribution   
Gene set null distribution of ES for REACTOME_INFLUENZA_LIFE_CYCLE