Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | chrom |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | REACTOME_GENERIC_TRANSCRIPTION_PATHWAY |
| Enrichment Score (ES) | 0.6247353 |
| Normalized Enrichment Score (NES) | 2.1973398 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.1904766E-4 |
| FWER p-Value | 0.001 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NR2F6 | NR2F6 Entrez, Source | nuclear receptor subfamily 2, group F, member 6 | 28 | 2.751 | 0.0753 | Yes |
| 2 | NCOR2 | NCOR2 Entrez, Source | nuclear receptor co-repressor 2 | 173 | 1.611 | 0.0814 | Yes |
| 3 | ESRRA | ESRRA Entrez, Source | estrogen-related receptor alpha | 220 | 1.457 | 0.1119 | Yes |
| 4 | HDAC1 | HDAC1 Entrez, Source | histone deacetylase 1 | 232 | 1.427 | 0.1520 | Yes |
| 5 | TGIF1 | 285 | 1.306 | 0.1763 | Yes | ||
| 6 | TEAD1 | TEAD1 Entrez, Source | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 294 | 1.283 | 0.2129 | Yes |
| 7 | UBE2D3 | UBE2D3 Entrez, Source | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 314 | 1.234 | 0.2447 | Yes |
| 8 | RXRB | RXRB Entrez, Source | retinoid X receptor, beta | 334 | 1.194 | 0.2753 | Yes |
| 9 | MEN1 | MEN1 Entrez, Source | multiple endocrine neoplasia I | 351 | 1.170 | 0.3061 | Yes |
| 10 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 357 | 1.150 | 0.3396 | Yes |
| 11 | MED12 | MED12 Entrez, Source | mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae) | 405 | 1.081 | 0.3584 | Yes |
| 12 | MED10 | MED10 Entrez, Source | mediator of RNA polymerase II transcription, subunit 10 homolog (NUT2, S. cerevisiae) | 453 | 0.996 | 0.3747 | Yes |
| 13 | MED1 | 526 | 0.919 | 0.3812 | Yes | ||
| 14 | ZKSCAN1 | ZKSCAN1 Entrez, Source | zinc finger with KRAB and SCAN domains 1 | 601 | 0.839 | 0.3847 | Yes |
| 15 | MED27 | 603 | 0.835 | 0.4097 | Yes | ||
| 16 | RBPJ | 605 | 0.834 | 0.4348 | Yes | ||
| 17 | MED20 | 606 | 0.833 | 0.4601 | Yes | ||
| 18 | NR1H2 | NR1H2 Entrez, Source | nuclear receptor subfamily 1, group H, member 2 | 634 | 0.804 | 0.4765 | Yes |
| 19 | CCNC | CCNC Entrez, Source | cyclin C | 649 | 0.789 | 0.4963 | Yes |
| 20 | NOTCH3 | NOTCH3 Entrez, Source | Notch homolog 3 (Drosophila) | 650 | 0.788 | 0.5202 | Yes |
| 21 | CDK9 | CDK9 Entrez, Source | cyclin-dependent kinase 9 (CDC2-related kinase) | 651 | 0.786 | 0.5441 | Yes |
| 22 | TBL1XR1 | TBL1XR1 Entrez, Source | transducin (beta)-like 1X-linked receptor 1 | 662 | 0.773 | 0.5647 | Yes |
| 23 | SP1 | SP1 Entrez, Source | Sp1 transcription factor | 755 | 0.688 | 0.5582 | Yes |
| 24 | MED4 | MED4 Entrez, Source | mediator of RNA polymerase II transcription, subunit 4 homolog (S. cerevisiae) | 761 | 0.686 | 0.5775 | Yes |
| 25 | MED31 | MED31 Entrez, Source | mediator of RNA polymerase II transcription, subunit 31 homolog (S. cerevisiae) | 788 | 0.665 | 0.5900 | Yes |
| 26 | MED17 | 792 | 0.662 | 0.6092 | Yes | ||
| 27 | MED24 | 807 | 0.648 | 0.6247 | Yes | ||
| 28 | MED16 | 1128 | 0.444 | 0.5430 | No | ||
| 29 | MED23 | 1210 | 0.403 | 0.5311 | No | ||
| 30 | ZNF460 | ZNF460 Entrez, Source | zinc finger protein 460 | 1336 | 0.321 | 0.5036 | No |
| 31 | NCOR1 | NCOR1 Entrez, Source | nuclear receptor co-repressor 1 | 1425 | 0.267 | 0.4855 | No |
| 32 | TRIM28 | TRIM28 Entrez, Source | tripartite motif-containing 28 | 1488 | 0.224 | 0.4739 | No |
| 33 | TFDP1 | TFDP1 Entrez, Source | transcription factor Dp-1 | 1602 | 0.151 | 0.4449 | No |
| 34 | MED15 | 1712 | 0.080 | 0.4149 | No | ||
| 35 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 1739 | 0.066 | 0.4091 | No |
| 36 | SNW1 | SNW1 Entrez, Source | SNW domain containing 1 | 1842 | 0.007 | 0.3790 | No |
| 37 | TRIM33 | TRIM33 Entrez, Source | tripartite motif-containing 33 | 1847 | 0.002 | 0.3778 | No |
| 38 | MED14 | 1927 | -0.057 | 0.3561 | No | ||
| 39 | E2F4 | E2F4 Entrez, Source | E2F transcription factor 4, p107/p130-binding | 1940 | -0.066 | 0.3545 | No |
| 40 | MED6 | MED6 Entrez, Source | mediator of RNA polymerase II transcription, subunit 6 homolog (S. cerevisiae) | 2104 | -0.183 | 0.3115 | No |
| 41 | MED25 | MED25 Entrez, Source | mediator of RNA polymerase II transcription, subunit 25 homolog (S. cerevisiae) | 2205 | -0.249 | 0.2893 | No |
| 42 | RBL1 | RBL1 Entrez, Source | retinoblastoma-like 1 (p107) | 2355 | -0.336 | 0.2552 | No |
| 43 | MED8 | MED8 Entrez, Source | mediator of RNA polymerase II transcription, subunit 8 homolog (S. cerevisiae) | 2510 | -0.468 | 0.2236 | No |
| 44 | CCNT1 | CCNT1 Entrez, Source | cyclin T1 | 3202 | -1.372 | 0.0595 | No |
