Datasetchrom
PhenotypeNoPhenotypeAvailable
Upregulated in classna_neg
GeneSetREACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS
Enrichment Score (ES)-0.49201617
Normalized Enrichment Score (NES)-1.4562619
Nominal p-value0.06081081
FDR q-value0.1145239
FWER p-Value0.957
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1OCLNOCLN
Entrez,  Source
occludin3891.099-0.0371No
2ADD1ADD1
Entrez,  Source
adducin 1 (alpha)4231.0380.0267No
3LMNB1LMNB1
Entrez,  Source
lamin B16930.7500.0004No
4CTNNB1CTNNB1
Entrez,  Source
catenin (cadherin-associated protein), beta 1, 88kDa13590.304-0.1746No
5DBNLDBNL
Entrez,  Source
drebrin-like15870.160-0.2303No
6DSG2DSG2
Entrez,  Source
desmoglein 218070.030-0.2929No
7STK24STK24
Entrez,  Source
serine/threonine kinase 24 (STE20 homolog, yeast)1879-0.021-0.3124No
8BCAP31BCAP31
Entrez,  Source
B-cell receptor-associated protein 312302-0.309-0.4152No
9LMNALMNA
Entrez,  Source
lamin A/C2563-0.509-0.4560Yes
10DSPDSP
Entrez,  Source
desmoplakin2578-0.522-0.4231Yes
11PLEC2765-0.684-0.4297Yes
12CDH1CDH1
Entrez,  Source
cadherin 1, type 1, E-cadherin (epithelial)2872-0.813-0.4034Yes
13CASP7CASP7
Entrez,  Source
caspase 7, apoptosis-related cysteine peptidase2922-0.871-0.3562Yes
14GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)2970-0.925-0.3046Yes
15TJP2TJP2
Entrez,  Source
tight junction protein 2 (zona occludens 2)3126-1.192-0.2660Yes
16SPTAN1SPTAN1
Entrez,  Source
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)3138-1.214-0.1833Yes
17TJP1TJP1
Entrez,  Source
tight junction protein 1 (zona occludens 1)3197-1.356-0.1044Yes
18VIMVIM
Entrez,  Source
vimentin3372-2.3260.0089Yes
Table: GSEA details [plain text format]



Fig 2: REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS: Random ES distribution   
Gene set null distribution of ES for REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS