Datasetchrom
PhenotypeNoPhenotypeAvailable
Upregulated in classna_pos
GeneSetREACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX
Enrichment Score (ES)0.78116864
Normalized Enrichment Score (NES)2.1379294
Nominal p-value0.0
FDR q-value9.886274E-4
FWER p-Value0.004
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1MCM2MCM2
Entrez,  Source		MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)592.3260.1001Yes
2MCM3MCM3
Entrez,  Source		MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)702.2230.2095Yes
3MCM6MCM6
Entrez,  Source		MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)792.1700.3168Yes
4ORC1942.0800.4178Yes
5MCM4MCM4
Entrez,  Source		MCM4 minichromosome maintenance deficient 4 (S. cerevisiae)1052.0440.5182Yes
6MCM5MCM5
Entrez,  Source		MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)1371.7810.5990Yes
7MCM7MCM7
Entrez,  Source		MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)1691.6220.6719Yes
8RPA2RPA2
Entrez,  Source		replication protein A2, 32kDa2341.4210.7248Yes
9POLA2POLA2
Entrez,  Source		polymerase (DNA directed), alpha 2 (70kD subunit)2741.3440.7812Yes
10CDK2CDK2
Entrez,  Source		cyclin-dependent kinase 26800.7590.7000No
11ORC59580.5460.6458No
12ORC39710.5380.6695No
13RPA1RPA1
Entrez,  Source		replication protein A1, 70kDa12800.3550.5965No
14ORC212980.3460.6090No
15RPA3RPA3
Entrez,  Source		replication protein A3, 14kDa2182-0.2330.3601No
Table: GSEA details [plain text format]



Fig 2: REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX: Random ES distribution   
Gene set null distribution of ES for REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX