Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | chrom |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S |
| Enrichment Score (ES) | -0.65158325 |
| Normalized Enrichment Score (NES) | -2.541087 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EIF3G | 187 | 1.581 | -0.0200 | No | ||
| 2 | EIF3B | 512 | 0.929 | -0.0957 | No | ||
| 3 | EIF4A2 | EIF4A2 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 2 | 737 | 0.706 | -0.1465 | No |
| 4 | EIF3K | 917 | 0.567 | -0.1871 | No | ||
| 5 | EIF3A | 1089 | 0.468 | -0.2276 | No | ||
| 6 | EIF4A1 | EIF4A1 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 1 | 1594 | 0.157 | -0.3744 | No |
| 7 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 1739 | 0.066 | -0.4159 | No |
| 8 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 1813 | 0.026 | -0.4371 | No |
| 9 | EIF3E | 1889 | -0.028 | -0.4588 | No | ||
| 10 | EIF3C | 1970 | -0.085 | -0.4808 | No | ||
| 11 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 1971 | -0.086 | -0.4788 | No |
| 12 | EIF3F | 2164 | -0.221 | -0.5311 | No | ||
| 13 | RPS24 | RPS24 Entrez, Source | ribosomal protein S24 | 2211 | -0.253 | -0.5391 | No |
| 14 | EIF3H | 2377 | -0.354 | -0.5803 | No | ||
| 15 | EIF3I | 2384 | -0.361 | -0.5740 | No | ||
| 16 | EIF4H | 2560 | -0.507 | -0.6147 | No | ||
| 17 | RPS8 | RPS8 Entrez, Source | ribosomal protein S8 | 2658 | -0.592 | -0.6302 | No |
| 18 | EIF3J | 2715 | -0.639 | -0.6325 | No | ||
| 19 | RPS15 | RPS15 Entrez, Source | ribosomal protein S15 | 2780 | -0.712 | -0.6355 | Yes |
| 20 | RPS7 | RPS7 Entrez, Source | ribosomal protein S7 | 2811 | -0.746 | -0.6275 | Yes |
| 21 | RPS5 | RPS5 Entrez, Source | ribosomal protein S5 | 2832 | -0.773 | -0.6160 | Yes |
| 22 | RPSA | RPSA Entrez, Source | ribosomal protein SA | 2843 | -0.783 | -0.6013 | Yes |
| 23 | RPS3A | RPS3A Entrez, Source | ribosomal protein S3A | 2847 | -0.786 | -0.5844 | Yes |
| 24 | EIF2S1 | EIF2S1 Entrez, Source | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | 2923 | -0.871 | -0.5871 | Yes |
| 25 | RPS13 | RPS13 Entrez, Source | ribosomal protein S13 | 2928 | -0.875 | -0.5684 | Yes |
| 26 | RPS9 | RPS9 Entrez, Source | ribosomal protein S9 | 2930 | -0.876 | -0.5489 | Yes |
| 27 | RPS10 | RPS10 Entrez, Source | ribosomal protein S10 | 2958 | -0.909 | -0.5364 | Yes |
| 28 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 2964 | -0.915 | -0.5172 | Yes |
| 29 | RPS25 | RPS25 Entrez, Source | ribosomal protein S25 | 2976 | -0.938 | -0.4992 | Yes |
| 30 | RPS29 | RPS29 Entrez, Source | ribosomal protein S29 | 2989 | -0.964 | -0.4810 | Yes |
| 31 | RPS6 | RPS6 Entrez, Source | ribosomal protein S6 | 2990 | -0.965 | -0.4591 | Yes |
| 32 | RPS3 | RPS3 Entrez, Source | ribosomal protein S3 | 2992 | -0.968 | -0.4375 | Yes |
| 33 | RPS11 | RPS11 Entrez, Source | ribosomal protein S11 | 2996 | -0.971 | -0.4164 | Yes |
| 34 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 3010 | -0.996 | -0.3978 | Yes |
| 35 | FAU | FAU Entrez, Source | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30 | 3011 | -0.998 | -0.3752 | Yes |
| 36 | EIF1AX | EIF1AX Entrez, Source | eukaryotic translation initiation factor 1A, X-linked | 3021 | -1.014 | -0.3549 | Yes |
| 37 | RPS23 | RPS23 Entrez, Source | ribosomal protein S23 | 3028 | -1.022 | -0.3336 | Yes |
| 38 | RPS18 | RPS18 Entrez, Source | ribosomal protein S18 | 3053 | -1.078 | -0.3163 | Yes |
| 39 | RPS16 | RPS16 Entrez, Source | ribosomal protein S16 | 3066 | -1.097 | -0.2951 | Yes |
| 40 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 3076 | -1.109 | -0.2726 | Yes |
| 41 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 3083 | -1.121 | -0.2491 | Yes |
| 42 | EIF2S2 | EIF2S2 Entrez, Source | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 3095 | -1.135 | -0.2267 | Yes |
| 43 | RPS4X | RPS4X Entrez, Source | ribosomal protein S4, X-linked | 3097 | -1.137 | -0.2012 | Yes |
| 44 | EIF3D | 3101 | -1.143 | -0.1762 | Yes | ||
| 45 | RPS21 | RPS21 Entrez, Source | ribosomal protein S21 | 3111 | -1.163 | -0.1526 | Yes |
| 46 | EIF2S3 | EIF2S3 Entrez, Source | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 3137 | -1.210 | -0.1327 | Yes |
| 47 | RPS12 | RPS12 Entrez, Source | ribosomal protein S12 | 3149 | -1.236 | -0.1080 | Yes |
| 48 | RPS28 | RPS28 Entrez, Source | ribosomal protein S28 | 3187 | -1.329 | -0.0890 | Yes |
| 49 | RPS15A | RPS15A Entrez, Source | ribosomal protein S15a | 3238 | -1.448 | -0.0711 | Yes |
| 50 | RPS26 | RPS26 Entrez, Source | ribosomal protein S26 | 3292 | -1.635 | -0.0499 | Yes |
| 51 | RPS20 | RPS20 Entrez, Source | ribosomal protein S20 | 3295 | -1.644 | -0.0133 | Yes |
| 52 | RPS27 | RPS27 Entrez, Source | ribosomal protein S27 (metallopanstimulin 1) | 3354 | -1.987 | 0.0143 | Yes |
