Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | chrom |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS |
| Enrichment Score (ES) | 0.69294703 |
| Normalized Enrichment Score (NES) | 2.0316691 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.00238513 |
| FWER p-Value | 0.014 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MCM2 | MCM2 Entrez, Source | MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae) | 59 | 2.326 | 0.0810 | Yes |
| 2 | MCM3 | MCM3 Entrez, Source | MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) | 70 | 2.223 | 0.1721 | Yes |
| 3 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 79 | 2.170 | 0.2615 | Yes |
| 4 | ORC1 | 94 | 2.080 | 0.3454 | Yes | ||
| 5 | MCM4 | MCM4 Entrez, Source | MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) | 105 | 2.044 | 0.4289 | Yes |
| 6 | MCM5 | MCM5 Entrez, Source | MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) | 137 | 1.781 | 0.4951 | Yes |
| 7 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 169 | 1.622 | 0.5546 | Yes |
| 8 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 234 | 1.421 | 0.5958 | Yes |
| 9 | RFC4 | RFC4 Entrez, Source | replication factor C (activator 1) 4, 37kDa | 447 | 1.003 | 0.5755 | Yes |
| 10 | ATR | ATR Entrez, Source | ataxia telangiectasia and Rad3 related | 494 | 0.950 | 0.6022 | Yes |
| 11 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 511 | 0.930 | 0.6368 | Yes |
| 12 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 594 | 0.851 | 0.6485 | Yes |
| 13 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 664 | 0.772 | 0.6608 | Yes |
| 14 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 680 | 0.759 | 0.6885 | Yes |
| 15 | RFC5 | RFC5 Entrez, Source | replication factor C (activator 1) 5, 36.5kDa | 764 | 0.685 | 0.6929 | Yes |
| 16 | ORC5 | 958 | 0.546 | 0.6590 | No | ||
| 17 | ORC3 | 971 | 0.538 | 0.6782 | No | ||
| 18 | RPA1 | RPA1 Entrez, Source | replication protein A1, 70kDa | 1280 | 0.355 | 0.6022 | No |
| 19 | ORC2 | 1298 | 0.346 | 0.6118 | No | ||
| 20 | RPA3 | RPA3 Entrez, Source | replication protein A3, 14kDa | 2182 | -0.233 | 0.3606 | No |
