Sample Final Questions:
1. The binding and coating
of the surfaces of invading microbes by either antibodies or C3b is
A) aided by the release of
cytokines by phagocytes
B) necessary for
phagocytosis of all microbes
C) called oposonization
D) responsible for the
direct lysis of invading microrganisms
Answer: C
2. Specific defenses
A) function against any
infectious agent
B) include phagocytes and
interferon
C) include only noncellular
defenses
D) respond to particular
infectious agents
Answer: D
3. Toll-like receptors can
distinguish between
A) nonspecific and specific
immune responses
B) gram-negative and
gram-positive bacteria
C) bacteria versus viruses
D) two of the above
Answer: D (items B and C are correct)
4. The mechanism of action
of interferon includes all of the following except
A) It binds to the surface
of uninfected cells
B) It inactivates viruses
C) It initiates manufacture
of another antiviral INF
D) It works in cells not
producing INF
E) None of the above
Answer: B
5. Colostrum which contains
large amounts of antibodies passed on to an infant from a mother during
breast-feeding, is an example of what type of immunity?
A) acquired active
artificial
B) acquired active natural
C) acquired passive natural
D) acquired passive
artificial
Answer: C
6. Most antigens are
A) large and complex
molecules
B) polysaccharides
C) are proteins with
molecular weights less than 10,000 Da
D) proteins that bind to a
specific antigenic determinant
Answer: A
7. Monoclonal antibodies are
all of the following except
A) antibodies that are
produced at greatest frequency in the body
B) made by hydridomas which
make only one specific antibody
C) produced by a clone of
cultured cells
D) used for diagnostic tests
and to treat rheumatoid arthritis
Answer: A
8. The following events
elicit an antibody response. What is the third step
A) Antigen-digest goes to surface of APC
B) APC phagocytizes antigen
C) B cell responds to
antigen
D) T-H cell recognizes
antigen-digest and MHC
E) T-H cell recognizes B cell
Answer: D
9. Which of the following
immune cells kills infected cells by releasing the lethal protein perforin?
A) NK cells
B) B cells
C) macrophages
D) TH2 cells
Answer: A
10. Which of the following
statements about immunological disorder is correct?
A) bottle-fed infants are
less likely to develop food allergies than are breast-fed infants
B) primary immunodeficiences
include malnutrition and AIDS
C) autoimmune disorders are
hypersensitivity reactions against self-antigens
D) secondary
immunodeficiences are genetic or developmental defects
Answer: C
11. A
test used to identify Streptococcus pyogenes in a patient is the
A) Direct fluorescent
antibody test
B) Indirect fluorescent
antibody test
C) None of the above
Answer: A
12. Purified protein
from B. pertusis is a(n)
A) Conjugated vaccine
B) Subunit vaccine
C) Toxoid vaccine
D) Attenuated whole-agent vaccine
Answer: B