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Total: 300 pts
Total: 300 pts


==Course Schedule==
==Tips for Success==
To maximize the your experience we strongly recommend the following strategies:
* Follow the directions for efficiently, finding high-impact papers, reading science research papers and preparing presentations.
* Read the papers, watch required videos and do the exercises regularly, long before you attend class.
* Attend all classes, as required.  Late arrival results in loss of points.
* Keep up with online exercises. Don’t wait until the due date to start tasks.
* Take notes or annotate slides while attending the lectures.
* Listen actively and participate in class and in online discussions. 
* Review and summarize material within 24 hrs after class.
* Observe the deadlines for submitting your work. Late submissions incur penalties.
* Put away cell phones, do not TM, email or play computer games in class.
 
==Hunter/CUNY Policies==
===Policy on Academic Integrity===
Hunter College regards acts of academic dishonesty (e.g., plagiarism, cheating on homework, online exercises or examinations, obtaining unfair advantage, and falsification of records and official documents) as serious offenses against the values of intellectual honesty.  The College is committed to enforcing the CUNY Policy on Academic Integrity, and we will pursue cases of academic dishonesty according to the Hunter College Academic Integrity Procedures.  Students will be asked to read this statement before exams.
===ADA Policy===
In compliance with the American Disability Act of 1990 (ADA) and with Section 504 of the Rehabilitation Act of 1973, Hunter College is committed to ensuring educational parity and accommodations for all students with documented disabilities and/or medical conditions. It is recommended that all students with documented disabilities (Emotional, Medical, Physical, and/or Learning) consult the Office of AccessABILITY, located in Room E1214B, to secure necessary academic accommodations. For further information and assistance, please call: (212) 772- 4857 or (212) 650-3230.
 
===Syllabus Policy==
Except for changes that substantially affect implementation of the evaluation (grading) statement, this syllabus is a guide for the course and is subject to change with advance notice, announced in class or posted on Blackboard.

Revision as of 02:13, 1 October 2019

BIOL47120 Biomedical Genomics II
Spring 2019
Instructor: Weigang Qiu, Ph.D.
Professor, Department of Biological Sciences, City University of New York, Hunter College & Graduate Center
Adjunct Faculty, Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weil Cornell Medical College
Office: B402 Belfer Research Building, 413 East 69th Street, New York, NY 10021, USA
Email: weigang@genectr.hunter.cuny.edu
Lab Website: http://diverge.hunter.cuny.edu/labwiki/

Course Overview

Welcome to Introductory BioMedical Genomics, a seminar course for advanced undergraduates and graduate students. A genome is the total genetic content of an organism. Driven by breakthroughs such as the decoding of the first human genome and rapid DNA and RNA-sequencing technologies, biomedical sciences are undergoing a rapid & irreversible transformation into a highly data-intensive field, that requires familiarity with concepts in both biology, computational, and data sciences.

Genome information is revolutionizing virtually all aspects of life sciences including basic research, medicine, and agriculture. Meanwhile, use of genomic data requires life scientists to be familiar with concepts and skills in biology, computer science, as well as data analysis.

This workshop is designed to introduce computational analysis of genomic data through hands-on computational exercises, using published studies.

The pre-requisites of the course are college-level courses in molecular biology, cell biology, and genetics. Introductory courses in computer programming and statistics are preferred but not strictly required.

Learning goals

By the end of this course successful students will be able to:

  • Describe next-generation sequencing (NGS) technologies & contrast it with traditional Sanger sequencing
  • Explain applications of NGS technology including pathogen genomics, cancer genomics, human genomic variation, transcriptomics, meta-genomics, epi-genomics, and microbiome.
  • Visualize and explore genomics data using RStudio
  • Replicate key results using a raw data set produced by a primary research paper

Web Links

Quizzes and Exams

Student performance will be evaluated by attendance, three (4) quizzes and a final report:

  • Attendance & In-class participation: 50 pts
  • Assignments: 5 x 10 = 50 pts
  • Quizzes: 2 x 25 pts = 50 pts
  • Mid-term: 50 pts
  • Final presentation & report: 100 pts

Total: 300 pts

Tips for Success

To maximize the your experience we strongly recommend the following strategies:

  • Follow the directions for efficiently, finding high-impact papers, reading science research papers and preparing presentations.
  • Read the papers, watch required videos and do the exercises regularly, long before you attend class.
  • Attend all classes, as required. Late arrival results in loss of points.
  • Keep up with online exercises. Don’t wait until the due date to start tasks.
  • Take notes or annotate slides while attending the lectures.
  • Listen actively and participate in class and in online discussions.
  • Review and summarize material within 24 hrs after class.
  • Observe the deadlines for submitting your work. Late submissions incur penalties.
  • Put away cell phones, do not TM, email or play computer games in class.

Hunter/CUNY Policies

Policy on Academic Integrity

Hunter College regards acts of academic dishonesty (e.g., plagiarism, cheating on homework, online exercises or examinations, obtaining unfair advantage, and falsification of records and official documents) as serious offenses against the values of intellectual honesty. The College is committed to enforcing the CUNY Policy on Academic Integrity, and we will pursue cases of academic dishonesty according to the Hunter College Academic Integrity Procedures. Students will be asked to read this statement before exams.

ADA Policy

In compliance with the American Disability Act of 1990 (ADA) and with Section 504 of the Rehabilitation Act of 1973, Hunter College is committed to ensuring educational parity and accommodations for all students with documented disabilities and/or medical conditions. It is recommended that all students with documented disabilities (Emotional, Medical, Physical, and/or Learning) consult the Office of AccessABILITY, located in Room E1214B, to secure necessary academic accommodations. For further information and assistance, please call: (212) 772- 4857 or (212) 650-3230.

=Syllabus Policy

Except for changes that substantially affect implementation of the evaluation (grading) statement, this syllabus is a guide for the course and is subject to change with advance notice, announced in class or posted on Blackboard.